澳大利亚 1998-2019 年与神经系统疾病相关的住院治疗情况：一项长期趋势分析。

Hospitalisations related to nervous-system diseases in Australia, 1998-2019: a secular trend analysis.

机构信息

Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, The University of Jordan, Amman, Jordan

Department of Pharmaceutical Sciences, Al Ain University College of Pharmacy, Abu Dhabi, UAE.

出版信息

BMJ Open. 2023 Sep 27;13(9):e074553. doi: 10.1136/bmjopen-2023-074553.

DOI:10.1136/bmjopen-2023-074553

PMID:37758673

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10537858/

Abstract

OBJECTIVE

The burden of neurological disease-related disabilities and deaths is one of the most serious issues globally. We aimed to examine the hospitalisation profile related to nervous system diseases in Australia for the duration between 1998 and 2019.

DESIGN

A secular trend analysis using a population-based dataset.

SETTING

This analysis used a population-based study of hospitalised patients in Australia. Hospitalisation data were extracted from the National Hospital Morbidity Database, which collects sets of episode-level information for Australian patients admitted to all private and public hospitals.

PARTICIPANTS

All patients who were hospitalised in all private and public hospitalisations.

PRIMARY OUTCOME MEASURE

Hospitalisation rates related to nervous system diseases.

RESULTS

Hospitalisation rates increased by 1.04 times (from 650.36 (95% CI 646.73 to 654.00) in 1998 to 1328.90 (95% CI 1324.44 to 1333.35) in 2019 per 100 000 persons, p<0.01). Overnight-stay episodes accounted for 57.0% of the total number of hospitalisations. Rates of the same-day hospitalisation for diseases of the nervous system increased by 2.10-fold (from 219.74 (95% CI 217.63 to 221.86) in 1998 to 680.23 (95% CI 677.03 to 683.43) in 2019 per 100 000 persons). Rates of overnight-stay hospital admission increased by 42.7% (from 430.62 (95% CI 427.66 to 433.58) in 1998 to 614.70 (95% CI 611.66 to 617.75) in 2019 per 100 000 persons). 'Episodic and paroxysmal disorders' were the most prevalent reason for hospitalisation, which accounted for 49.0% of the total number of episodes. Female hospitalisation rates increased by 1.13-fold (from 618.23 (95% CI 613.24 to 623.22) in 1998 to 1316.33 (95% CI 1310.07 to 1322.58) in 2019 per 100 000 persons). Male hospitalisation rates increased by 86.4% (from 682.95 (95% CI 677.67 to 688.23) in 1998 to 1273.18 (95% CI 1266.98 to 1279.37) in 2019 per 100 000 persons).

CONCLUSION

Hospitalisation rates for neurological disorders in Australia are high, potentially owing to the ageing of the population. Males had greater rates of hospitalisation than females.

摘要

目的

神经疾病相关残疾和死亡的负担是全球最严重的问题之一。我们旨在研究澳大利亚神经系统疾病住院患者的住院情况，时间范围为 1998 年至 2019 年。

设计

使用基于人群的数据集进行的时间趋势分析。

设置

本分析使用澳大利亚住院患者的基于人群的研究。住院数据从国家医院发病率数据库中提取，该数据库收集了所有私立和公立医院入院患者的一系列病例水平信息。

参与者

所有在所有私立和公立医院住院的患者。

主要观察指标

与神经系统疾病相关的住院率。

结果

住院率增加了 1.04 倍（从 1998 年的 650.36（95%CI 646.73-654.00）增至 2019 年的 1328.90（95%CI 1324.44-1333.35）/100000 人，p<0.01）。过夜住院占总住院人数的 57.0%。神经系统疾病的当日住院率增加了 2.10 倍（从 1998 年的 219.74（95%CI 217.63-221.86）增至 2019 年的 680.23（95%CI 677.03-683.43）/100000 人）。过夜住院入院率增加了 42.7%（从 1998 年的 430.62（95%CI 427.66-433.58）增至 2019 年的 614.70（95%CI 611.66-617.75）/100000 人）。“发作性和阵发性疾病”是住院的最常见原因，占总病例数的 49.0%。女性住院率增加了 1.13 倍（从 1998 年的 618.23（95%CI 613.24-623.22）增至 2019 年的 1316.33（95%CI 1310.07-1322.58）/100000 人）。男性住院率增加了 86.4%（从 1998 年的 682.95（95%CI 677.67-688.23）增至 2019 年的 1273.18（95%CI 1266.98-1279.37）/100000 人）。