Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Canada.
Research center of the Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Clin Auton Res. 2023 Dec;33(6):791-810. doi: 10.1007/s10286-023-00986-2. Epub 2023 Sep 27.
Patients with dysautonomia often experience symptoms such as dizziness, syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the cerebrovasculature to react to transient changes in arterial blood pressure, could be associated with these symptoms.
In this narrative review, we go beyond the classical view of cerebral autoregulation to discuss dynamic cerebral autoregulation, focusing on recent advances pitfalls and future directions.
Following some historical background, this narrative review provides a brief overview of the concept of cerebral autoregulation, with a focus on the quantification of dynamic cerebral autoregulation. We then discuss the main protocols and analytical approaches to assess dynamic cerebral autoregulation, including recent advances and important issues which need to be tackled.
The researcher or clinician new to this field needs an adequate comprehension of the toolbox they have to adequately assess, and interpret, the complex relationship between arterial blood pressure and cerebral blood flow in healthy individuals and clinical populations, including patients with autonomic disorders.
自主神经功能障碍患者常出现头晕、晕厥、视力模糊和脑雾等症状。动态脑自动调节，即脑血管对动脉血压瞬态变化的反应能力，可能与这些症状有关。
在这篇叙述性综述中，我们超越了经典的脑自动调节观点，讨论了动态脑自动调节，重点介绍了最近的进展、陷阱和未来方向。
在一些历史背景之后，本叙述性综述简要概述了脑自动调节的概念，重点是动态脑自动调节的量化。然后，我们讨论了评估动态脑自动调节的主要方案和分析方法，包括最近的进展和需要解决的重要问题。
对于这个领域的新手研究人员或临床医生来说，他们需要充分理解他们必须具备的工具，以充分评估和解释健康个体和临床人群（包括自主神经障碍患者）之间动脉血压和脑血流之间的复杂关系。
