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口腔拟杆菌致脑脓肿 1 例报告及文献复习

A case report of a brain abscess due to prevotella oris and a review of the literature.

机构信息

Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.

Department of Neurology, Tianjin Huanhu Hosipital, 6 Jizhao Rd, Tianjin, 300350, China.

出版信息

BMC Infect Dis. 2023 Sep 27;23(1):633. doi: 10.1186/s12879-023-08306-9.

DOI:10.1186/s12879-023-08306-9
PMID:37759232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10523687/
Abstract

BACKGROUND

Brain abscesses caused by Prevotella oris are rarely reported. Here, we described a case of a brain infection caused by Prevotella oris that was detected by metagenomic next-generation sequencing (mNGS).

CASE PRESENTATION

A 63-year-old man with no medical history reported headache in the right frontotemporal region, fever, and intermittent diplopia. Magnetic resonance imaging (MRI) revealed abnormal signals and enhancement changes in the superior sellar region. mNGS testing showed that cerebrospinal fluid collected from the spine was positive for Prevotella oris. After receiving a combined treatment of antibiotic therapy, the patient recovered well.

CONCLUSION

We reviewed the relevant literature and summarized the characteristics and prognosis of this type of bacterial infection to provide ideas for clinicians to diagnose and treat this disease.

摘要

背景

由口腔普雷沃菌引起的脑脓肿很少见。在这里,我们通过宏基因组下一代测序(mNGS)描述了一例由口腔普雷沃菌引起的脑感染病例。

病例介绍

一名 63 岁男性,无既往病史,诉右额颞部头痛、发热和间歇性复视。磁共振成像(MRI)显示鞍上区异常信号和增强改变。mNGS 检测显示从脊柱采集的脑脊液呈口腔普雷沃菌阳性。接受抗生素联合治疗后,患者恢复良好。

结论

我们复习了相关文献,总结了此类细菌感染的特点和预后,为临床医生诊断和治疗该病提供思路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/8c27a10bdc98/12879_2023_8306_Figc_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/6ec52c7eaa8d/12879_2023_8306_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/ab0311c052a4/12879_2023_8306_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/8c27a10bdc98/12879_2023_8306_Figc_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/6ec52c7eaa8d/12879_2023_8306_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/ab0311c052a4/12879_2023_8306_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1520/10523687/8c27a10bdc98/12879_2023_8306_Figc_HTML.jpg

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Brain abscesses caused by anaerobic bacteria.
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Prevotella: An insight into its characteristics and associated virulence factors.普雷沃氏菌属:对其特征及相关毒力因子的深入了解。
Microb Pathog. 2022 Aug;169:105673. doi: 10.1016/j.micpath.2022.105673. Epub 2022 Jul 15.
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