Anderson I E
Vet Microbiol. 1986 Sep;12(3):213-20. doi: 10.1016/0378-1135(86)90050-7.
Virulence associated with five ovine isolates of Chlamydia psittaci was compared using a mouse model. Comparable doses of each isolate were inoculated via the footpad into separate groups of 6-week-old mice. Four isolates from abortion were judged more virulent than an isolate from arthritis because of their ability to migrate from the site of infection to the spleen. Similar results were obtained using three different mouse strains. Re-isolation of C. psittaci indicated variation in susceptibility to infection between different mouse strains.
使用小鼠模型比较了五株鹦鹉热衣原体绵羊分离株的毒力。将每种分离株的等量剂量通过足垫接种到单独的6周龄小鼠组中。由于四株来自流产的分离株能够从感染部位迁移到脾脏,因此被判定比一株来自关节炎的分离株毒力更强。使用三种不同的小鼠品系也获得了类似的结果。鹦鹉热衣原体的再次分离表明不同小鼠品系对感染的易感性存在差异。