中加两国两种不同父本猪的生长性能及血浆代谢组学比较

Comparison of Growth Performance and Plasma Metabolomics between Two Sire-Breeds of Pigs in China.

机构信息

Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.

Key Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, College of Animal and Technology, Sichuan Agricultural University, Chengdu 611130, China.

出版信息

Genes (Basel). 2023 Aug 27;14(9):1706. doi: 10.3390/genes14091706.

DOI:10.3390/genes14091706

PMID:37761845

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10531030/

Abstract

The Yorkshire pigs, renowned for their remarkable growth rate, low feed conversion ratio (FCR), and high meat production, emerge as a novel preference for paternal breeding. In this study, we found that purebred paternal Yorkshire pigs (PY) surpass the purebred Duroc breed in terms of growth rate. Specifically, purebred PY attain a weight of 100 kg at an earlier age compared to purebred Duroc (Male, 145.07 vs. 162.91; Female, 145.91 vs. 167.57; -value < 0.01). Furthermore, different hybrid combinations suggest that offspring involving purebred PY exhibit superior growth performance. Compared with purebred Duroc, the offspring of purebred PY have an earlier age in days (173.23 vs. 183.54; -value < 0.05) at the same slaughter weight. The changes of plasma metabolites of 60-day-old purebred boars in the two sire-breeds showed that 1335 metabolites in plasma were detected. Compared with Duroc, 28 metabolites were down-regulated and 49 metabolites were up-regulated in PY. Principal component analysis (PCA) discerned notable dissimilarities in plasma metabolites between the two sire-breeds of pigs. The levels of glycerol 3-phosphate choline, cytidine, guanine, and arachidonic acid increased significantly (-value < 0.05), exerting an impact on their growth and development. According to our results, PY could be a new paternal option as a terminal sire in three-way cross system.

摘要

大约克夏猪以其出色的生长速度、低饲料转化率（FCR）和高肉质生产而闻名，成为父本繁殖的新选择。在这项研究中，我们发现纯系父本大约克夏猪（PY）在生长速度方面优于纯系杜洛克猪。具体而言，纯系 PY 达到 100 公斤体重的年龄比纯系杜洛克猪早（雄性，145.07 对 162.91；雌性，145.91 对 167.57；-值 < 0.01）。此外，不同的杂交组合表明，涉及纯系 PY 的后代表现出优异的生长性能。与纯系杜洛克猪相比，纯系 PY 的后代在相同的屠宰体重下，达到日龄（173.23 对 183.54；-值 < 0.05）更早。两个父本品种 60 日龄纯系公猪血浆代谢物的变化表明，在血浆中检测到 1335 种代谢物。与杜洛克猪相比，PY 中有 28 种代谢物下调，49 种代谢物上调。主成分分析（PCA）区分了两个父本品种猪血浆代谢物之间的显著差异。甘油 3-磷酸胆碱、胞苷、鸟嘌呤和花生四烯酸的水平显著升高（-值 < 0.05），对其生长和发育产生影响。根据我们的结果，PY 可以作为三元杂交系统中的终端父本成为一个新的选择。