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使用三维反转恢复真实重建（3D-REAL-IR）序列对单侧确诊梅尼埃病患者前庭内淋巴积水进行磁共振容积定量分析。

Magnetic Resonance Volumetric Quantification of Vestibular Endolymphatic Hydrops in Patients with Unilateral Definite Meniere's Disease Using 3D Inversion Recovery with Real Reconstruction (3D-REAL-IR) Sequence.

作者信息

Suárez-Vega Víctor, Manrique-Huarte Raquel, Dominguez Pablo, Blanco Melissa, Alonso-Burgos Alberto, Pérez-Fernández Nicolás

机构信息

Department of Radiology, Clinica Universidad de Navarra, 28027 Madrid, Spain.

Department of Otorhinolaryngology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.

出版信息

J Clin Med. 2023 Sep 14;12(18):5965. doi: 10.3390/jcm12185965.

DOI:10.3390/jcm12185965
PMID:37762906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10532400/
Abstract

BACKGROUND

The 3D-REAL-IR MRI sequence allows for an in vivo visualization of endolymphatic hydrops. Qualitative assessment methods of the severity of vestibular and cochlear hydrops are the most commonly used.

METHODS

A quantitative volumetric measurement of vestibular EH in patients with definite unilateral Ménière's disease using the 3D-REAL-IR sequence and the calculation of the endolymphatic ratio (ELR) was intended.

RESULTS

Volumetric calculations of the vestibules, vestibular endolymph and vestibular ELR are performed in 96 patients with unilateral Ménière's disease and correlated with classic qualitative grading scales.

CONCLUSIONS

Quantitative volumetric measurement of vestibular hydrops using the 3D-REAL-IR sequence is feasible and reproducible in daily clinical practice. Vestibular ELR values exceeding 60% defined radiologically significant vestibular hydrops, while values below 30% defined radiologically non-significant vestibular hydrops.

摘要

背景

3D-REAL-IR MRI序列可实现内淋巴积水的活体可视化。前庭和耳蜗积水严重程度的定性评估方法是最常用的。

方法

旨在使用3D-REAL-IR序列对确诊为单侧梅尼埃病的患者进行前庭内淋巴积水的定量容积测量，并计算内淋巴比率（ELR）。

结果

对96例单侧梅尼埃病患者进行了前庭、前庭内淋巴和前庭ELR的容积计算，并与经典的定性分级量表进行了相关性分析。

结论

在日常临床实践中，使用3D-REAL-IR序列对前庭积水进行定量容积测量是可行且可重复的。放射学上，ELR值超过60%定义为显著前庭积水，而值低于30%定义为非显著前庭积水。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/030dc947e8b9/jcm-12-05965-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/89f2e66b9c27/jcm-12-05965-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/e4eccce5e8c7/jcm-12-05965-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/c287ce8f12a2/jcm-12-05965-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/030dc947e8b9/jcm-12-05965-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/89f2e66b9c27/jcm-12-05965-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/e4eccce5e8c7/jcm-12-05965-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/c287ce8f12a2/jcm-12-05965-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5afe/10532400/030dc947e8b9/jcm-12-05965-g004.jpg

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本文引用的文献

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J Int Adv Otol. 2021 Nov;17(6):536-540. doi: 10.5152/iao.2021.21317.
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Novel Magnetic Resonance Imaging-Based Method for Accurate Diagnosis of Meniere's Disease.基于磁共振成像的梅尼埃病准确诊断新方法。
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Endolymphatic Hydrops in Fluctuating Hearing Loss and Recurrent Vertigo.波动性听力损失和复发性眩晕中的内淋巴积水
磁共振成像（MRI）检测到的内淋巴积水是否真的是以耳蜗为中心的表现？
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Direct Visualization of Tracer Permeation into the Endolymph in Human Patients Using MR Imaging.使用磁共振成像直接可视化示踪剂渗透到人类患者内淋巴中的情况。
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Modulation of hearing function following the downgrading or upgrading of endolymphatic hydrops in Meniere's disease patients with endolymphatic duct blockage.膜迷路积水内淋巴液引流受阻的梅尼埃病患者中内淋巴液减少或增多对听力功能的调节。
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