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妊娠期阻塞性睡眠呼吸暂停与小于胎龄儿分娩的关系——一项系统评价

A Relation between Obstructive Sleep Apnea in Pregnancy and Delivering Small for Gestational Age Infant-A Systematic Review.

作者信息

Grajczyk Alicja, Dżaman Karolina, Czerwaty Katarzyna, Kasperczak Monika, Zgliczyńska Magdalena, Stępień Anna, Kosińska-Kaczyńska Katarzyna

机构信息

Department of Otolaryngology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.

Department of Obstetrics, Perinatology and Neonatology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.

出版信息

J Clin Med. 2023 Sep 14;12(18):5972. doi: 10.3390/jcm12185972.

Abstract

Obstructive sleep apnea (OSA) during pregnancy can negatively affect both the mother and the baby. Our main goal is to show whether there is an association between OSA during pregnancy and delivering small for gestational age (SGA) infants. This systematic review was conducted according to the PRISMA 2020 statement using three databases: MEDLINE via PubMed, Scopus, and Cochrane Library. All databases were last accessed on 1 June 2023. The implemented systematic literature search identified 744 articles. After excluding reviews, meta-analyses, book chapters, case reports, and letters, 47 studies were analyzed, 18 of which finally met the inclusion criteria. The included studies mainly indicate that OSA during pregnancy may not significantly impact SGA, but some of them have shown the existence of this relation. Nevertheless, it is recommended that all pregnant women should be screened for symptoms of OSA and that sleep tests should be performed on those who show signs of it. Detecting and treating OSA early in pregnancy can help reduce the condition's negative effects. However, more extensive studies are still needed to gather clear evidence on the impact of an OSA diagnosis on mothers and babies.

摘要

妊娠期阻塞性睡眠呼吸暂停(OSA)会对母亲和胎儿均产生负面影响。我们的主要目标是探究妊娠期OSA与小于胎龄(SGA)儿分娩之间是否存在关联。本系统评价依据PRISMA 2020声明,使用三个数据库进行:通过PubMed检索MEDLINE、Scopus和Cochrane图书馆。所有数据库的最后访问时间为2023年6月1日。实施的系统文献检索共识别出744篇文章。在排除综述、荟萃分析、书籍章节、病例报告和信函后,对47项研究进行了分析,其中18项最终符合纳入标准。纳入的研究主要表明,妊娠期OSA可能不会对SGA产生显著影响,但其中一些研究显示了这种关联的存在。尽管如此,建议对所有孕妇进行OSA症状筛查,并对有症状迹象的孕妇进行睡眠测试。在妊娠早期检测和治疗OSA有助于减轻该病症的负面影响。然而,仍需要更广泛的研究来收集关于OSA诊断对母亲和婴儿影响的确切证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab68/10532405/ad84138df44d/jcm-12-05972-g001.jpg

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