School of Public Health, Taipei Medical University, Taipei, Taiwan.
Am J Obstet Gynecol. 2012 Feb;206(2):136.e1-5. doi: 10.1016/j.ajog.2011.09.006. Epub 2011 Sep 16.
We examined the risk of adverse pregnancy outcomes, including low birthweight (LBW), preterm birth, small for gestational age (SGA), cesarean section (CS), low Apgar score (at 5 minutes after delivery), and preeclampsia in pregnant women with and without obstructive sleep apnea (OSA).
Our subjects included 791 women with OSA and 3955 randomly selected women without OSA. We performed conditional logistic regression analyses to examine the risks of adverse pregnancy outcomes between women with and without OSA.
Compared with women without OSA, adjusted odds ratios for LBW, preterm birth, SGA infants, CS, and preeclampsia in women with OSA were 1.76 (95% confidence interval [CI], 1.28-2.40), 2.31 (95% CI, 1.77-3.01), 1.34 (95% CI, 1.09-1.66), 1.74 (95% CI, 1.48-2.04), and 1.60 (95% CI, 2.16-11.26), respectively.
Pregnant women with OSA are at increased risk for having LBW, preterm, and SGA infants, CS, and preeclampsia, compared with pregnant women without OSA.
我们研究了患有阻塞性睡眠呼吸暂停（OSA）和无阻塞性睡眠呼吸暂停（OSA）的孕妇不良妊娠结局（包括低出生体重（LBW）、早产、小于胎龄儿（SGA）、剖宫产（CS）、出生后 5 分钟低 Apgar 评分和子痫前期）的风险。
我们的研究对象包括 791 名患有 OSA 的女性和 3955 名随机选择的无 OSA 的女性。我们进行了条件逻辑回归分析，以检查 OSA 女性与无 OSA 女性之间不良妊娠结局的风险。
与无 OSA 的女性相比，患有 OSA 的女性 LBW、早产、SGA 婴儿、CS 和子痫前期的调整比值比分别为 1.76（95%置信区间[CI]，1.28-2.40）、2.31（95% CI，1.77-3.01）、1.34（95% CI，1.09-1.66）、1.74（95% CI，1.48-2.04）和 1.60（95% CI，2.16-11.26）。
与无 OSA 的孕妇相比，患有 OSA 的孕妇发生 LBW、早产和 SGA 婴儿、CS 和子痫前期的风险增加。
