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侧向扩散反应:揭示治愈性半面痉挛的关键证据

Lateral Spread Response: Unveiling the Smoking Gun for Cured Hemifacial Spasm.

作者信息

Cho Kyung Rae, Park Sang Ku, Park Kwan

机构信息

Department of Neurosurgery, Konkuk University Medical Center, Seoul 05030, Republic of Korea.

Department of Neurosurgery, School of Medicine Sungkyunkwan University, Seoul 16419, Republic of Korea.

出版信息

Life (Basel). 2023 Aug 29;13(9):1825. doi: 10.3390/life13091825.

Abstract

Hemifacial spasm (HFS) is a rare disorder characterized by involuntary facial muscle contractions. The primary cause is mechanical compression of the facial nerve by nearby structures. Lateral spread response (LSR) is an abnormal muscle response observed during electromyogram (EMG) testing and is associated with HFS. Intraoperative monitoring of LSR is crucial during surgery to confirm successful decompression. Proper anesthesia and electrode positioning are important for accurate LSR monitoring. Stimulation parameters should be carefully adjusted to avoid artifacts. The disappearance of LSR during surgery is associated with short-term outcomes, but its persistence does not necessarily indicate poor long-term outcomes. LSR monitoring has both positive and negative prognostic value, and its predictive ability varies across studies. Early disappearance of LSR can occur before decompression and may indicate better clinical outcomes. Further research is needed to fully understand the implications of LSR monitoring in HFS surgery.

摘要

面肌痉挛(HFS)是一种罕见的疾病,其特征为面部肌肉不自主收缩。主要病因是附近结构对面神经的机械性压迫。侧方扩散反应(LSR)是在肌电图(EMG)测试中观察到的一种异常肌肉反应,与面肌痉挛相关。手术中对LSR进行监测对于确认减压是否成功至关重要。适当的麻醉和电极定位对于准确监测LSR很重要。应仔细调整刺激参数以避免伪迹。手术过程中LSR的消失与短期预后相关,但其持续存在并不一定表明长期预后不良。LSR监测具有正性和负性预后价值,其预测能力在不同研究中有所不同。LSR的早期消失可能在减压之前出现,并且可能预示更好的临床结果。需要进一步研究以充分了解LSR监测在面肌痉挛手术中的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e0/10532564/97af06190449/life-13-01825-g001.jpg

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