Song Hongmei, Xu Songbai, Fan Xiushuang, Yu Mingxin, Feng Jiachun, Sun Lichao
Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Department of Anesthesiology, The First Hospital of Jilin University, Changchun, Jilin, China.
J Int Med Res. 2019 Dec;47(12):6120-6128. doi: 10.1177/0300060519839526. Epub 2019 Apr 14.
This study aimed to investigate the prognostic value of the lateral spread response (LSR) for predicting surgical outcomes following microvascular decompression (MVD) in patients with hemifacial spasm.
Seventy-three patients with hemifacial spasm underwent MVD with intraoperative LSR monitoring. Surgical outcomes were evaluated 1 week and 1 year after MVD and correlations between LSR characteristics and surgical outcomes were analyzed.
The LSR disappeared completely in 61 patients during surgery (Group A; prior to insertion of Teflon felt pledgets in 11, after insertion of pledgets in 50), disappeared partially in nine patients (Group B), and remained unchanged in three patients (Group C). Fifty-five patients showed short-term and 61 patients showed long-term clinical cures during the follow-up period. The short-term and long-term cure rates were significantly higher in Group A than in Group C. There was no correlation between the time of complete LSR disappearance and surgical outcomes.
Disappearance of the LSR during MVD is correlated with the surgical outcomes. Intraoperative LSR monitoring is a reliable approach for predicting the prognosis of hemifacial spasm following MVD, but the time at which LSR disappears is not a prognostic indicator.
本研究旨在探讨面肌痉挛患者微血管减压术（MVD）中侧方扩散反应（LSR）对预测手术结果的预后价值。
73例面肌痉挛患者接受了术中LSR监测的MVD手术。在MVD术后1周和1年评估手术结果，并分析LSR特征与手术结果之间的相关性。
61例患者术中LSR完全消失（A组；11例在插入明胶海绵垫之前，50例在插入明胶海绵垫之后），9例患者部分消失（B组），3例患者无变化（C组）。随访期间，55例患者短期临床治愈，61例患者长期临床治愈。A组的短期和长期治愈率显著高于C组。LSR完全消失的时间与手术结果之间无相关性。
MVD术中LSR消失与手术结果相关。术中LSR监测是预测MVD术后面肌痉挛预后的可靠方法，但LSR消失的时间不是预后指标。
