Division of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.
Medicina (Kaunas). 2023 Aug 22;59(9):1506. doi: 10.3390/medicina59091506.
Muscle cramps are often observed in patients with liver diseases, especially advanced liver fibrosis. The exact prevalence of muscle cramps in outpatients with liver diseases in Japan is unknown. This study examined the prevalence of, and therapies for, muscle cramps in outpatients with liver diseases in Tokyo, Japan. A total of 238 outpatients with liver diseases were retrospectively examined. We investigated whether they had muscle cramps using a visual analog scale (VAS) (from 0, none, to 10, strongest), and also investigated their therapies. Muscle cramps were observed in 34 outpatients with liver diseases (14.3%); their mean VAS score was 5.53. A multivariate analysis demonstrated that older age (equal to or older than 66 years) was the only significant factor as-sociated with muscle cramps. The prevalence of muscle cramps among patients with liver diseases seemed not to be higher. The problem was that only 11 (32.4%) of 34 outpatients received therapy for their muscle cramps. Only age is related to muscle cramps, which is rather weak, and it is possible that this common symptom may not be limited to liver disease patients.
肌肉痉挛在肝病患者中很常见，尤其是在晚期肝纤维化患者中。日本肝病门诊患者肌肉痉挛的确切患病率尚不清楚。本研究在日本东京检查了肝病门诊患者肌肉痉挛的患病率和治疗方法。共回顾性检查了 238 名肝病门诊患者。我们使用视觉模拟量表（VAS）（从 0 分，无，到 10 分，最强）来检查他们是否有肌肉痉挛，并调查了他们的治疗方法。34 名肝病门诊患者（14.3%）出现肌肉痉挛；他们的 VAS 评分平均为 5.53。多变量分析表明，年龄较大（等于或大于 66 岁）是与肌肉痉挛唯一相关的显著因素。肝病患者肌肉痉挛的患病率似乎没有更高。问题是，只有 34 名患者中的 11 名（32.4%）接受了肌肉痉挛的治疗。只有年龄与肌肉痉挛有关，而且强度较弱，这种常见症状可能不仅限于肝病患者。
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