Cardiology Department, Ankara Bilkent City Hospital, 06800 Ankara, Turkey.
Cardiology Department, Bandırma Onyedi Eylul University, 10200 Balıkesir, Turkey.
Medicina (Kaunas). 2023 Sep 15;59(9):1666. doi: 10.3390/medicina59091666.
: Aortic stenosis (AS) is a widespread valvular disease in developed countries, primarily among the elderly. Transcatheter aortic valve replacement (TAVR) has become a viable alternative to aortic valve surgery for patients with severe AS who are deemed a high surgical risk or for whom the AS is found to be inoperable. Predicting outcomes after TAVR is essential. The Naples Prognostic Score (NPS) is a new scoring method that evaluates nutritional status and inflammation. Our study is aims to examine the relationship between the NPS and outcomes for patients receiving TAVR. : We conducted a retrospective study of 370 patients who underwent TAVR across three tertiary medical centres from March 2019 to March 2023. The patients were divided into two groups based on their NPS, namely, low (0, 1, and 2) and high (3 and 4). Our study is primarily aimed to determine the one-year mortality rate. : Within one year, the mortality rate for the entire group was 8.6%. Nonetheless, the low-NPS group had a rate of 5.0%, whereas the high-NPS group had a rate of 13%. The difference between the two groups was statistically significant, with a -value of 0.06. : Our results show that NPS is an independent predictor of one-year mortality in patients undergoing TAVR.
主动脉瓣狭窄（AS）是发达国家一种广泛存在的瓣膜疾病，主要发生在老年人中。经导管主动脉瓣置换术（TAVR）已成为严重 AS 患者的一种可行替代方法，这些患者被认为手术风险高，或 AS 无法手术。预测 TAVR 后的结果至关重要。那不勒斯预后评分（NPS）是一种新的评分方法，可评估营养状况和炎症。我们的研究旨在探讨 NPS 与接受 TAVR 的患者结局之间的关系。
我们对 2019 年 3 月至 2023 年 3 月在三个三级医疗中心接受 TAVR 的 370 名患者进行了回顾性研究。根据 NPS 将患者分为两组，即低（0、1 和 2）和高（3 和 4）组。我们的研究主要目的是确定一年的死亡率。
在一年内，整个组的死亡率为 8.6%。然而，低 NPS 组的死亡率为 5.0%，而高 NPS 组的死亡率为 13%。两组之间的差异具有统计学意义，p 值为 0.06。
我们的结果表明，NPS 是 TAVR 后患者一年死亡率的独立预测因子。
