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[大脑血管病变中的闭锁综合征]

[Locked-in syndrome in vascular pathology of the brain].

作者信息

Erokhina L G, Gubskiĭ L V, Khalatov V S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(9):1284-90.

PMID:3776405
Abstract

Seven patients with vascular abnormalities of the brain (infarct of the ventral portions of the pons varolii and/or the midbrain--5, hemorrhage into the base of the pons varolii--1 and transient impairment of the cerebral circulation in the vertebro-basilar system--presented the locked-in syndrome with such underlying disorders as tetraplegia with the maintenance of tendon and the appearance of abnormal plantar muscle reflexes, pseudobulbar syndrome with intact consciousness and the absence of any significant changes in the EEG. Other findings included disorders of eye movement, mainly in the horizontal plane and involuntary muscular activity such as forced crying, decerebrational and decorticational muscular spasms, as well as masticatory automatisms. The authors emphasize the identity of the given syndrome and Filimonov's syndrome which was repeatedly described in Soviet literature before 1966 when the term "locked-in syndrome" was proposed. They also discuss the pathogenetic mechanisms of the development of the locked-in syndrome in occlusion of the basilar artery.

摘要

7例脑部血管异常患者(脑桥腹侧部和/或中脑梗死5例、脑桥基底部出血1例、椎基底动脉系统短暂性脑循环障碍1例)呈现闭锁综合征,伴有四肢瘫但保留腱反射、出现异常跖肌反射等基础疾病,以及意识清醒的假性球麻痹综合征且脑电图无任何显著变化。其他表现包括眼球运动障碍,主要为水平方向,以及非自主性肌肉活动,如强迫性哭笑、去大脑和去皮层性肌肉痉挛,还有咀嚼自动症。作者强调该综合征与1966年提出“闭锁综合征”这一术语之前苏联文献中多次描述的菲利莫诺夫综合征相同。他们还讨论了基底动脉闭塞时闭锁综合征发生发展的发病机制。

相似文献

1
[Locked-in syndrome in vascular pathology of the brain].[大脑血管病变中的闭锁综合征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(9):1284-90.
2
[Locked-in syndrome. Report of a case and review of the literature].[闭锁综合征。1例报告及文献复习]
Arq Neuropsiquiatr. 1982 Sep;40(3):296-300.
3
Perfusion and diffusion tensor imaging in a patient with locked-in syndrome after neurosurgical vascular bypass and endovascular embolization of a basilar artery aneurysm: case report.基底动脉动脉瘤神经外科血管搭桥和血管内栓塞术后闭锁综合征患者的灌注和扩散张量成像:病例报告
Neurosurgery. 2006 Apr;58(4):E794; discussion E794. doi: 10.1227/01.NEU.0000204893.07192.1F.
4
[A case of vertebro-vertebral syndrome indicating multiple extracranial vascular pathology].[一例提示多发性颅外血管病变的椎-椎综合征]
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