Stiller C R, Sinclair N R
Transplant Proc. 1979 Mar;11(1):343-9.
Rejection in non-identical pairs is both antibody- and cell-mediated. Measurements of CDC and LMC specific for the donor can be useful clinical tools in confirming rejection, detecting periods of likely rejection, and helping to predict responses to therapy. In particular, the LMC assay appears to have excellent temporal correlations with graft status. Rejection in the HLA-identical sibling transplant is directed against a non-MHC antigen, is cell-mediated, and can be typed for using CTL.
非同卵配对移植中的排斥反应是由抗体和细胞介导的。针对供体的补体依赖细胞毒性（CDC）和淋巴细胞介导的细胞毒性（LMC）检测，在确认排斥反应、检测可能发生排斥反应的时期以及帮助预测治疗反应方面，可能是有用的临床工具。特别是，LMC检测似乎与移植物状态具有良好的时间相关性。 HLA相同的同胞移植中的排斥反应是针对非主要组织相容性复合体（MHC）抗原的，是由细胞介导的，并且可以使用细胞毒性T淋巴细胞（CTL）进行分型。
