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巴氯芬和普萘洛尔用于治疗一名桥脑出血患者的神经源性发热:病例报告

Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report.

作者信息

Poudel Saroj, Chalise Rupak, Bist Manoj, Regmi Ashim, Ghimire Anup, Khanal Kishor

机构信息

Critical Care Medicine Nepal Mediciti Lalitpur Nepal.

出版信息

Clin Case Rep. 2023 Sep 25;11(9):e7956. doi: 10.1002/ccr3.7956. eCollection 2023 Sep.

Abstract

KEY CLINICAL MESSAGE

Neurogenic fever (NF) is a potentially life-threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF.

ABSTRACT

Neurogenic fever (NF) is a common complication following pontine hemorrhage and poses significant challenges for clinicians in terms of diagnosis, management, and patient outcomes. This study delves into the efficacy of treatment methods involving baclofen and propranolol for neurogenic fever in patients with pontine hemorrhage. The results demonstrated a significant reduction in the duration and intensity of fever. Moreover, the treatment modality was well-tolerated and devoid of any adverse effects. These findings suggest that the use of oral baclofen and propranolol may be a promising therapeutic option for managing neurogenic fever in patients with pontine hemorrhage.

摘要

关键临床信息

神经源性发热(NF)是桥脑出血患者常见的一种潜在危及生命的并发症。本病例报告强调了口服巴氯芬和普萘洛尔作为治疗神经源性发热的有效治疗策略的成功应用。

摘要

神经源性发热(NF)是桥脑出血后的常见并发症,在诊断、管理和患者预后方面给临床医生带来重大挑战。本研究探讨了巴氯芬和普萘洛尔治疗桥脑出血患者神经源性发热的疗效。结果表明发热的持续时间和强度显著降低。此外,该治疗方式耐受性良好,未出现任何不良反应。这些发现表明,口服巴氯芬和普萘洛尔可能是治疗桥脑出血患者神经源性发热的一种有前景的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66a7/10520415/50bd25f1e39c/CCR3-11-e7956-g002.jpg

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