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巨细胞病毒(CMV)驱动的转化:中枢神经系统假瘤的罕见病因。

Cytomegalovirus (CMV)-Driven Transformation: An Uncommon Cause of a Central Nervous System Pseudotumor.

作者信息

Tejada-Pineda María Fernanda, Hoyo-Ulloa Irma, Ortega-Porcayo Luis Alberto, Baquera-Heredia Jesús J, Zárate-García José Pablo, Romano-Feinholz Samuel, Ponce-Gómez Juan Antonio, Jiménez Sergio M

机构信息

Neurological Surgery, ABC Medical Center, Mexico City, MEX.

Infectious Disease, ABC Medical Center, Mexico City, MEX.

出版信息

Cureus. 2023 Aug 27;15(8):e44188. doi: 10.7759/cureus.44188. eCollection 2023 Aug.

DOI:10.7759/cureus.44188
PMID:37767259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10520896/
Abstract

Cytomegalovirus (CMV) is an opportunistic virus that can cause life-threatening neurological diseases in immunocompromised individuals, particularly those with HIV/AIDS. In this case report, a patient presenting with left gait lateralization was found to have a ring-enhancing cerebral mass lesion that was attributed to CMV. To date, only eight similar cases have been documented. When evaluating patients with HIV/AIDS who have cerebral mass lesions, clinicians should keep CMV as a possible cause because prompt antiviral therapy may improve clinical outcomes.

摘要

巨细胞病毒(CMV)是一种机会性病毒,可在免疫功能低下的个体中引发危及生命的神经系统疾病,尤其是那些感染了艾滋病毒/艾滋病的患者。在本病例报告中,一名出现左侧步态偏斜的患者被发现有一个环状强化的脑实质占位性病变,病因被归结为巨细胞病毒。迄今为止,仅有八例类似病例被记录在案。在评估患有脑实质占位性病变的艾滋病毒/艾滋病患者时,临床医生应将巨细胞病毒视为可能的病因,因为及时进行抗病毒治疗可能会改善临床预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d7f/10520896/873590f1efd9/cureus-0015-00000044188-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d7f/10520896/a12e113a18e6/cureus-0015-00000044188-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d7f/10520896/873590f1efd9/cureus-0015-00000044188-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d7f/10520896/a12e113a18e6/cureus-0015-00000044188-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d7f/10520896/873590f1efd9/cureus-0015-00000044188-i02.jpg

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A comparison of brain biopsy and CSF-PCR in the diagnosis of CNS lesions in AIDS patients.艾滋病患者中枢神经系统病变诊断中脑活检与脑脊液聚合酶链反应的比较。
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AIDS-associated cytomegalovirus infection mimicking central nervous system tumors: a diagnostic challenge.
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Cerebral mass lesions due to cytomegalovirus in patients with AIDS: report of two cases.艾滋病患者中由巨细胞病毒引起的脑实质病变:两例报告
J Infect. 1995 Mar;30(2):147-51. doi: 10.1016/s0163-4453(95)80010-7.