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[富血小板血浆在喉和颈段气管瘢痕性狭窄治疗中的应用]

[The use of platelet-rich plasma in the treatment of cicatricial stenosis of the larynx and cervical trachea].

作者信息

Kirasirova E A, Yumatova D A, Mamedov R F, Lafutkina N V, Rezakov R A, Mironova D A

机构信息

Pirogov Russian National Research Medical University, Moscow, Russia.

Sverzhevsky Research Clinical Institute for Otolaryngology, Moscow, Russia.

出版信息

Vestn Otorinolaringol. 2023;88(4):73-80. doi: 10.17116/otorino20228804173.

Abstract

Despite the technical achievements of recent years in medicine, the problem of frequent recurrent stricture formation of the lumen of larynx and cervical trachea remains urgent. The etiology and pathogenesis of development of scar stenosis of the larynx and trachea were considered, and the analysis of the drugs' use for topical therapy in the comprehensive treatment of this pathology was conducted in the presented review. Special attention was paid to plasma enriched with platelets, its use in otorhinolaryngology, in particular in the treatment of laryngeal diseases. Positive and negative sides of the adjuvant therapy use have been identified. The search for means helping to prevent recurrent stricture formation of laryngeal lumen and cervical trachea determines the interest of the considered problem.

摘要

尽管近年来医学在技术上取得了诸多成就,但喉腔和颈段气管频繁复发性狭窄形成的问题仍然十分紧迫。本文综述探讨了喉气管瘢痕狭窄的病因及发病机制,并对该病症综合治疗中局部治疗药物的使用情况进行了分析。特别关注了富含血小板的血浆及其在耳鼻喉科的应用,尤其是在治疗喉部疾病方面。已明确了辅助治疗使用的利弊。寻求有助于预防喉腔和颈段气管复发性狭窄形成的方法决定了人们对该问题的关注。

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