Department of Neurosurgery, University of Florida, PO Box 100265, Gainesville, FL, 32610, USA.
College of Medicine, University of Florida, Gainesville, FL, USA.
Eur Spine J. 2023 Nov;32(11):3868-3874. doi: 10.1007/s00586-023-07954-4. Epub 2023 Sep 28.
Predicting urinary retention is difficult. The aim of this study is to prospectively validate a previously developed model using machine learning techniques.
Patients were recruited from pre-operative clinic. Prediction of urinary retention was completed pre-operatively by 4 individuals and compared to ground truth POUR outcomes. Inter-rater reliability was calculated with intercorrelation coefficient (2,1).
171 patients were included with age 63 ± 14 years, 58.5% (100/171) male, BMI 30.4 ± 5.9 kg/m, American Society of Anesthesiologists class 2.6 ± 0.5, 1.7 ± 1.0 levels, 56% (96/171) fusions. The observed rate of POUR was 25.7%. The model's performance was found to be 0.663 (0.567-0.759). With a regression model probability cutoff of 0.24 and a neural network cutoff of 0.23, the following predictive power was achieved: specificity 90.6%, sensitivity 22.7%, negative predictive value 77.2%, positive predictive value 45.5%, and accuracy 73.1%. Intercorrelation coefficient for the regression aspect of the model was found to be 0.889 and intercorrelation coefficient for the neural network aspect of the model was found to be 0.874.
This prospective study confirms performance of the prediction model for POUR developed with retrospective data, showing great correlation. This supports the use of machine learning techniques in the prediction of postoperative complications such as urinary retention.
预测尿潴留较为困难。本研究旨在通过机器学习技术对先前开发的模型进行前瞻性验证。
患者从术前门诊招募。术前由 4 名个体完成尿潴留预测,并与真实的 POUR 结果进行比较。采用组内相关系数(2,1)计算组内相关性。
共纳入 171 例患者,年龄 63±14 岁,58.5%(100/171)为男性,BMI 30.4±5.9kg/m2,美国麻醉医师协会(ASA)分级 2.6±0.5 级,1.7±1.0 节段,56%(96/171)为融合手术。观察到的 POUR 发生率为 25.7%。模型的性能为 0.663(0.567-0.759)。当回归模型概率截断值为 0.24 且神经网络截断值为 0.23 时,可获得以下预测能力:特异性 90.6%,敏感性 22.7%,阴性预测值 77.2%,阳性预测值 45.5%和准确率 73.1%。回归模型方面的组内相关系数为 0.889,神经网络模型方面的组内相关系数为 0.874。
本前瞻性研究证实了使用回顾性数据开发的 POUR 预测模型的性能,相关性较好。这支持了机器学习技术在预测术后并发症(如尿潴留)方面的应用。