Mental Health, Alcohol, Substance Use and Tobacco Drug Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Department of Psychiatry and Mental Health, Division of Addiction Psychiatry, University of Cape Town, Groote Schuur Hospital, Observatory, Cape Town, South Africa.
PLoS One. 2023 Sep 28;18(9):e0290781. doi: 10.1371/journal.pone.0290781. eCollection 2023.
Little is known about sexual and gender minority youth (SGMY) who have sex with men's unique patterns of substance use, even though they are at risk for substance use and adverse mental and other health outcomes. We used latent class analysis to examine typologies of substance use and multinomial logistic regression to investigate mental health outcomes (depression and anxiety) and HIV/STI testing correlates associated with different classes of substance use in a sample of SGMY who have sex with men in the USA and use substances (n = 414) who participated in an online survey. The average age was 22.50 years old (SD = 3.22). A four-class solution was identified representing: 'depressant and stimulant use' (3.4%), 'high polysubstance use' (4.6%), 'low substance use with moderate cannabis use' (79.2%), and 'high cannabis, stimulant and alcohol use' (12.8%). Membership to a specified substance use class varied by age, previous arrest, gender identity, anxiety, and lifetime HIV testing. Multivariate logistic regression results indicated that participants in the high polysubstance use (AOR = 5.48, 95% CI 1.51, 19.97) and high cannabis use class (AOR = 3.87, 95% CI 1.25, 11.94) were significantly more likely than those in the low substance use with moderate cannabis use class to report previous arrest. Those in the high polysubstance use class were also significantly less likely to have been tested for HIV than those in the low substance use with moderate cannabis use class (AOR = 0.21, 95% CI 0.05, 0.93). Findings will guide the development and implementation of tailored approaches to addressing the intersection of substance use and HIV risk among SGMY.
关于与男性发生性行为的性少数和性别少数青年（SGMY）的物质使用独特模式，人们知之甚少，尽管他们存在物质使用和不良心理及其他健康问题的风险。我们使用潜在类别分析来检查物质使用的类型学，并使用多项逻辑回归来研究心理健康结果（抑郁和焦虑）以及与美国与男性发生性行为的 SGMY 中不同物质使用类别相关的 HIV/性传播感染检测相关性，这些 SGMY 参与者使用物质（n = 414）并参与了一项在线调查。平均年龄为 22.50 岁（SD = 3.22）。确定了一个四种类别解决方案，代表：“使用抑郁药和兴奋剂”（3.4%）、“高度多物质使用”（4.6%）、“低物质使用和中度大麻使用”（79.2%）和“高大麻、兴奋剂和酒精使用”（12.8%）。特定物质使用类别的成员资格因年龄、先前被捕、性别认同、焦虑和终身 HIV 检测而异。多变量逻辑回归结果表明，高多物质使用类别的参与者（AOR = 5.48，95%CI 1.51，19.97）和高大麻使用类别的参与者（AOR = 3.87，95%CI 1.25，11.94）比低物质使用和中度大麻使用类别的参与者更有可能报告先前被捕。与低物质使用和中度大麻使用类别的参与者相比，高多物质使用类别的参与者也不太可能接受 HIV 检测（AOR = 0.21，95%CI 0.05，0.93）。这些发现将指导为 SGMY 制定和实施针对物质使用和 HIV 风险交叉问题的量身定制方法。
