糖尿病患者的肾移植——再探讨

Renal transplantation in patients with diabetes mellitus--revisited.

作者信息

Zincke H, Woods J E, Sterioff S, Johnson W J, Palumbo P J, Mitchell J C, Frohnert P P, Anderson C F, Service F J, Leary F J

出版信息

Transplant Proc. 1979 Mar;11(1):55-9.

PMID:377694

Abstract

Sixty-one patients with end-stage renal failure due to diabetic nephropathy received 68 renal allografts from June 1970 to February 1978. Patient and graft survival results equaled those for nondiabetic patients, as reported by the Human Renal Transplant Registry (HRTR). Renal allografts from siblings or pretreated cadaver donors had a significantly longer survival time than did allografts from nonpretreated cadaver donors. It is concluded that renal transplantation with living related and pretreated cadaver donor kidneys continues to be the treatment of choice and is superior to other forms of treatment in the insulin-dependent diabetic patient with end-stage renal disease.

摘要

1970年6月至1978年2月期间，61例因糖尿病肾病导致终末期肾衰竭的患者接受了68次肾移植。如人类肾移植登记处（HRTR）所报告的那样，患者和移植肾的存活结果与非糖尿病患者相当。来自兄弟姐妹或经过预处理的尸体供者的肾移植，其存活时间明显长于来自未经预处理的尸体供者的移植肾。得出的结论是，对于患有终末期肾病的胰岛素依赖型糖尿病患者，亲属活体肾移植和经过预处理的尸体供肾移植仍然是首选治疗方法，并且优于其他治疗方式。