Hui Christy Lai Ming, Wong Charlie Cheuk Lam, Chan Evie Wai Ting, Suen Yi Nam, Chan Sherry Kit Wa, Lee Edwin Ho Ming, Chang Wing Chung, Chen Eric Yu Hai
Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region of China.
Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region of China.
Psychiatry Res. 2023 Oct;328:115487. doi: 10.1016/j.psychres.2023.115487. Epub 2023 Sep 22.
The impact of Coronavirus Disease 2019 (COVID-19) on psychiatric care in remitted patients with first-episode psychosis (FEP) remains unknown. This study compared the demographic, clinical, functional, and cognitive profiles of patients recruited before and during the pandemic. The results showed that COVID patients were significantly older, smokers, alcohol users, experienced more stressors, with better functioning than pre-COVID patients. The former also had fewer severe negative and general psychopathological symptoms, more impaired insight, poorer medication compliance, and worse cognitive performance. Our findings highlighted a timely need to improve awareness into the illness and treatment in FEP patients experiencing pandemic related stressors.
2019年冠状病毒病（COVID-19）对首次发作精神病（FEP）缓解期患者精神科护理的影响尚不清楚。本研究比较了大流行之前和期间招募的患者的人口统计学、临床、功能和认知特征。结果显示，感染COVID的患者年龄显著更大，有吸烟、饮酒习惯，经历更多应激源，功能状况比感染COVID之前的患者更好。前者还具有较少的严重阴性和一般精神病理症状，自知力损害更多，服药依从性更差，认知表现更糟。我们的研究结果突出表明，对于经历与大流行相关应激源的FEP患者，迫切需要提高对疾病和治疗的认识。
