Defining Clinically Meaningful Cut Points for Leg Power Impairment Using Physical Performance in Older Adults: A Secondary Analysis From Boston RISE.

OBJECTIVE

To identify clinically meaningful thresholds of leg power impairment identified by the stair climb power test (SCPT).

DESIGN

Cross-sectional analysis using the baseline data from an observational cohort study.

SETTING

The Boston Rehabilitative Impairment Study of the Elderly.

PARTICIPANTS

Community-dwelling older adults (N=413).

MAIN OUTCOME MEASURES

SCPT and the Short Physical Performance Battery (SPPB).

RESULTS

Using the receiver operating characteristic curves and Youden's J statistics, the optimal threshold for the SCPT associated with mobility limitation as defined by an SPPB score ≤9 was 3.07 Watts/kg for men with a sensitivity of 74%, a specificity of 73% and, an area under the curve (AUC) value of 0.78. For women, the optimal threshold was 2.59 Watts/kg with a sensitivity of 83%, a specificity of 69%, and an AUC value of 0.81. The classification and regression tree sensitivity analysis demonstrated similar thresholds, 2.88 Watts/kg and 2.53 Watts/kg for men and women, respectively.

CONCLUSIONS

The study identified clinically meaningful thresholds of impairment for the SCPT for mobility limited older primary care patients. These thresholds may be used to inform rehabilitation care to improve functional mobility of older adults and should be validated in larger more representative clinical trials.