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亡羊补牢,为时未晚:即使在长时间清醒后,睡眠仍能支持记忆巩固。

Better late than never: sleep still supports memory consolidation after prolonged periods of wakefulness.

机构信息

Max Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195 Berlin, Germany

Max Planck University College London Centre for Computational Psychiatry and Aging Research, 14195 Berlin, Germany.

出版信息

Learn Mem. 2023 Sep 28;30(9):245-249. doi: 10.1101/lm.053660.122. Print 2023 Sep.

DOI:10.1101/lm.053660.122
PMID:37770107
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10547377/
Abstract

While the benefits of sleep for associative memory are well established, it is unclear whether single-item memories profit from overnight consolidation to the same extent. We addressed this question in a preregistered, online study and also investigated how the temporal proximity between learning and sleep influences overnight retention. Sleep relative to wakefulness improved retention of item and associative memories to similar extents irrespective of whether sleep occurred soon after learning or following a prolonged waking interval. Our findings highlight the far-reaching influences of sleep on memory that can arise even after substantial periods of wakefulness.

摘要

虽然睡眠对联想记忆的益处已得到充分证实,但目前尚不清楚单项记忆是否同样受益于夜间巩固。我们在一项预先注册的在线研究中解决了这个问题,还研究了学习和睡眠之间的时间接近程度如何影响夜间记忆保留。与清醒状态相比,无论睡眠是在学习后不久发生还是在长时间清醒间隔后发生,睡眠都能以相似的程度提高项目和联想记忆的保留。我们的研究结果强调了睡眠对记忆的深远影响,即使在长时间清醒之后也能产生这种影响。

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本文引用的文献

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Cortical-hippocampal coupling during manifold exploration in motor cortex.在运动皮层的多种探索中皮质-海马耦合。
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Sleep spindles track cortical learning patterns for memory consolidation.睡眠纺锤波追踪皮层学习模式以促进记忆巩固。
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