阿魏属芳香药用植物阿魏的染色体水平参考基因组。

A chromosome-level reference genome of an aromatic medicinal plant Adenosma buchneroides.

机构信息

Department of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.

Key Laboratory of Research and Utilization of Ethnomedicinal Plant Resources of Hunan Province, College of Biological and Food Engineering, Huaihua University, Huaihua, 418000, China.

出版信息

Sci Data. 2023 Sep 28;10(1):660. doi: 10.1038/s41597-023-02571-8.

DOI:10.1038/s41597-023-02571-8

PMID:37770464

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10539347/

Abstract

Adenosma buchneroides Bonati, belonging to the genus Adenosum (Plantaginaceae), is an aromatic medicinal plant and utilized in traditional Chinese medicine. It has been widely used as plant-based repellents to prevent vector-borne diseases. However, the lack of a reference genome limits the study of conservation management and molecular biology of A. buchneroides. Here, we generated a chromosome-level de novo genome assembly of A. buchneroides which is a high-quality chromosome-scale assembly of aromatic medicinal plant in Plantaginaceae. The genome has a total length of 442.84 Mb with scaffold N50 of 27.98 Mb and 95.55% of the genome assigned to 14 chromosomes. BUSCO assessment yielded a completeness score of 97.2%. Furthermore, we predicted 24,367 protein-coding genes, and 95.79% of them was functionally annotated. The chromosome-scale genome of A. buchneroides will be a significant resource for understanding the genetic basis and evolution of active components biosynthesis, which will facilitate further study and exploit of A. buchneroides.

摘要

琴叶茜草 Adenosma buchneroides Bonati，属于琴叶茜草属（车前科），是一种芳香药用植物，在中国传统医学中被广泛应用。它已被广泛用作植物驱避剂，以预防媒介传播疾病。然而，缺乏参考基因组限制了对 A. buchneroides 的保护管理和分子生物学的研究。在这里，我们生成了 A. buchneroides 的染色体水平从头基因组组装，这是车前科芳香药用植物的高质量染色体规模组装。基因组总长为 442.84 Mb，支架 N50 为 27.98 Mb，95.55%的基因组被分配到 14 条染色体上。BUSCO 评估得出的完整性得分为 97.2%。此外，我们预测了 24367 个蛋白质编码基因，其中 95.79%具有功能注释。A. buchneroides 的染色体水平基因组将是理解活性成分生物合成遗传基础和进化的重要资源，这将有助于进一步研究和开发 A. buchneroides。