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台湾骨盆和/或髋臼骨折患者深静脉血栓和症状性肺栓塞的发生率:一项回顾性研究。

Incidence of deep vein thrombosis and symptomatic pulmonary embolism in Taiwanese patients with pelvic and/or acetabular fractures: a retrospective study.

机构信息

Department of Orthopaedics, New Taipei Municipal TuCheng Hospital, No. 6, Sec. 2, Jincheng Rd., Tucheng Dist., New Taipei City, 236, Taiwan.

Chang Gung University, No. 259, Wenhua 1St Rd., Guishan Dist., Taoyuan City, 33302, Taiwan.

出版信息

Sci Rep. 2023 Sep 28;13(1):16352. doi: 10.1038/s41598-023-43449-4.

Abstract

Venous thromboembolism (VTE) is common in patients with trauma, and thromboprophylaxis has been advocated. However, conflicting results regarding VTE rates in the Asian population following orthopaedic procedures have been presented. We aimed to investigate the VTE incidence in Taiwanese patients with pelvic and/or acetabular fractures and identify the associated risk factors. We included 402 patients who underwent surgery for pelvic and/or acetabular fractures. All patients received mechanical thromboprophylaxis with graduated compression stockings. Duplex scanning was performed postoperatively or during follow-up when signs or symptoms of deep vein thrombosis (DVT) developed. Variables with a significance level of ≤ 0.1 in the univariate analyses were introduced into the multivariate logistic regression analysis to identify DVT risk factors. The overall DVT and symptomatic pulmonary embolism (PE) rate was 3.48% (14/402 patients). Among patients with DVT, 46.1% were asymptomatic. Patients with VTE were significantly older than those without. Multivariate logistic regression analysis revealed that age was a VTE risk factor. The incidence of DVT and symptomatic PE in our cohort was low. Advanced age was a risk factor for VTE. These findings could help clinicians develop appropriate prevention and treatment strategies for VTE in Taiwanese patients with pelvic and/or acetabular fractures.

摘要

静脉血栓栓塞症(VTE)在创伤患者中很常见,已提倡进行血栓预防。然而,关于亚洲人群在骨科手术后 VTE 发生率的结果存在矛盾。我们旨在调查台湾骨盆和/或髋臼骨折患者的 VTE 发生率,并确定相关的危险因素。我们纳入了 402 例接受骨盆和/或髋臼骨折手术的患者。所有患者均接受机械性血栓预防,使用分级加压弹力袜。术后或出现深静脉血栓(DVT)症状或体征时进行双功能超声检查。单因素分析中具有≤0.1 显著性水平的变量被引入多因素逻辑回归分析,以确定 DVT 的危险因素。总体 DVT 和有症状的肺栓塞(PE)发生率为 3.48%(14/402 例患者)。在 DVT 患者中,46.1%为无症状。有 VTE 的患者明显比没有 VTE 的患者年龄更大。多因素逻辑回归分析显示,年龄是 VTE 的危险因素。我们队列中的 DVT 和有症状的 PE 发生率较低。高龄是 VTE 的危险因素。这些发现可以帮助临床医生为台湾骨盆和/或髋臼骨折患者制定适当的 VTE 预防和治疗策略。

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