Azegami M, Mori N
Am J Obstet Gynecol. 1986 Nov;155(5):1119-24. doi: 10.1016/0002-9378(86)90362-5.
Extracts of experimental amniotic fluid embolism from rabbit lungs showed the same biologic activities as leukotrienes and a peak on high-performance liquid chromatography at the same retention time as leukotriene D4. Acute death was prevented by administration of 5-lipoxygenase inhibitor. These results suggest the possibility that leukotrienes contribute to the clinical and pathophysiologic features of amniotic fluid embolism.
从兔肺中提取的实验性羊水栓塞样本显示出与白三烯相同的生物活性，并且在高效液相色谱上的峰值与白三烯D4的保留时间相同。通过给予5-脂氧合酶抑制剂可预防急性死亡。这些结果提示白三烯可能参与羊水栓塞的临床和病理生理特征。
