Isha Shahin, Sharma Rohan, Hannon Rachel M, Sanghavi Devang K
Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Department of Neurology and Neuro Critical Care, Mayo Clinic, Jacksonville, Florida, USA.
Oxf Med Case Reports. 2023 Sep 25;2023(9):omad089. doi: 10.1093/omcr/omad089. eCollection 2023 Sep.
Carditis is a rare complication of Lyme disease and usually presents in the early dissemination phase, several weeks after exposure to a tick bite. Conduction abnormalities are the most common manifestation of Lyme carditis. The presentation can vary from atrioventricular conduction delay (first-degree atrioventricular conduction block) to life-threatening situations, such as a complete heart block. Although such manifestations occur late, our case report describes an interesting case where the patient developed a complete heart block in the setting of acute Lyme disease. An elevated IgM with negative IgG Lyme serology titer, an unusual finding, initially led us to face a diagnostic dilemma. Our suspicion of a tick bite was affirmed when we detected a positive titer for , an organism carried by the same tick and a common co-infection with Lyme disease. The patient improved with antibiotic therapy and temporary pacemaker support during the initial few days of admission.
心脏炎是莱姆病的一种罕见并发症,通常出现在疾病早期传播阶段,即蜱虫叮咬暴露数周后。传导异常是莱姆病心脏炎最常见的表现形式。其表现可从房室传导延迟(一度房室传导阻滞)到危及生命的情况,如完全性心脏传导阻滞。尽管此类表现出现较晚,但我们的病例报告描述了一个有趣的病例,该患者在急性莱姆病背景下发生了完全性心脏传导阻滞。IgM升高且莱姆病血清学IgG滴度为阴性,这一不寻常的发现最初使我们面临诊断困境。当我们检测到 (一种由同一种蜱虫携带且常与莱姆病共同感染的病原体)的阳性滴度时,则证实了我们对蜱虫叮咬的怀疑。患者在入院最初几天接受抗生素治疗和临时起搏器支持后病情好转。