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一例免疫功能正常患者创伤后皮肤感染播散所致的肺诺卡菌病病例。

A case of pulmonary nocardiosis with spread from a post-traumatic cutaneous infection in an immunocompetent patient.

作者信息

Iwabayashi Masaaki, Takiguchi Junji, Tomioka Hiromi

机构信息

Department of Respiratory Medicine Kobe City Medical Center West Hospital Kobe Japan.

出版信息

Respirol Case Rep. 2023 Sep 26;11(10):e01227. doi: 10.1002/rcr2.1227. eCollection 2023 Oct.

Abstract

is an aerobic Gram-positive bacterium found in the environment, including soil and water. is reportedly associated with cutaneous infections, and disseminated disease is typically detected in immunocompromised individuals. We present a rare case of disseminated nocardiosis with in an immunocompetent patient. An 82-year-old male, who had a left elbow injury 2 months prior to the first visit, presented with bilateral multiple lung nodules. was identified in both sputum and pus specimens, we concluded that the had spread from the primary cutaneous lesion. The patient was treated with antibiotics and had a favourable clinical course. As the present case report demonstrates, disseminated nocardiosis caused by this species can progress from a primary cutaneous lesion even in immunocompetent individuals, if the initiation of appropriate treatment is delayed. Therefore, careful evaluation is warranted when species are detected.

摘要

是一种在环境中发现的需氧革兰氏阳性菌,包括土壤和水中。据报道,它与皮肤感染有关,并且通常在免疫功能低下的个体中检测到播散性疾病。我们报告了一例免疫功能正常患者发生播散性诺卡菌病伴[此处原文缺失相关内容]的罕见病例。一名82岁男性,在首次就诊前2个月左肘部受伤,出现双侧多个肺结节。在痰液和脓液标本中均鉴定出[此处原文缺失相关内容],我们得出结论,[此处原文缺失相关内容]已从原发性皮肤病变扩散。患者接受了抗生素治疗,临床过程良好。正如本病例报告所示,如果延迟开始适当治疗,即使在免疫功能正常的个体中,由该菌种引起的播散性诺卡菌病也可从原发性皮肤病变发展而来。因此,当检测到[此处原文缺失相关内容]菌种时,有必要进行仔细评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/923b/10522963/144bacdeed20/RCR2-11-e01227-g001.jpg

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