Huang Yuan, Fu Yong, Sun Jing, Xu Bin, Wu Lei, Tang Lan-Fang
Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Department of Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Front Pediatr. 2023 Sep 12;11:1232185. doi: 10.3389/fped.2023.1232185. eCollection 2023.
Pulmonary mucoepidermoid carcinoma (PMEC) is a rare tumor, particularly in children, and its clinical manifestations vary. When the tumor is small, it may be asymptomatic; however, with larger tumors, patients may present with symptoms such as recurring pneumonia, atelectasis, persistent cough, chest pain, and even hemoptysis. PMEC appears as an exophytic intrabronchial mass. This study aims to report on the clinical manifestations, imaging findings, treatment approaches, and prognosis of two children diagnosed with PMEC at our hospital between January 2018 and December 2022. The age of onset for both children was 9 years, and the masses were located in the right upper lobe bronchi. Following surgical treatment, both patients showed a good prognosis. In addition, we conducted a comprehensive review of the relevant literature to enhance the overall understanding of PMEC.
肺黏液表皮样癌（PMEC）是一种罕见肿瘤，在儿童中尤为少见，其临床表现各异。肿瘤较小时可能无症状；然而，肿瘤较大时，患者可能出现反复肺炎、肺不张、持续性咳嗽、胸痛甚至咯血等症状。PMEC表现为支气管内的外生性肿块。本研究旨在报告2018年1月至2022年12月期间在我院确诊为PMEC的两名儿童的临床表现、影像学表现、治疗方法及预后。两名儿童的发病年龄均为9岁，肿块位于右上叶支气管。手术治疗后，两名患者均预后良好。此外，我们对相关文献进行了全面综述，以加深对PMEC的整体认识。
