Raina Dimple, Husain Uneza, Kumar Pavneesh, Pandita Ajay K, Negi Nidhi
Microbiology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, IND.
Microbiology, Government Doon Medical College, Dehradun, IND.
Cureus. 2023 Aug 28;15(8):e44263. doi: 10.7759/cureus.44263. eCollection 2023 Aug.
Osteomyelitis, an infection related to bone and bone marrow, is very diverse in its pathophysiology and clinical presentation; hence, it is considered one of the most difficult-to-treat infections. The present study is aimed at assessing the microbiological profile of osteomyelitis and related antimicrobial susceptibility patterns in patients attending a tertiary care center in Uttarakhand, India, over a period of one year (January to December 2019). In aerobic culture, 58/105 (55.2%) bacterial isolates were detected. In addition, was the most common isolate, and amongst Gram-negative bacilli, most isolates that grew on culture were (22.4%). Out of 21 isolates, methicillin resistance was detected in nine [9/21 (42%)] cases, which is a matter of concern. Hence, proper training and application of antimicrobial stewardship are the need of the hour so that clinicians can initiate targeted therapy as early as possible.
骨髓炎是一种与骨骼和骨髓相关的感染，其病理生理学和临床表现非常多样；因此，它被认为是最难治疗的感染之一。本研究旨在评估印度北阿坎德邦一家三级医疗中心的患者在一年时间（2019年1月至12月）内骨髓炎的微生物谱及相关抗菌药敏模式。在需氧培养中，检测到58/105（55.2%）的细菌分离株。此外， 是最常见的分离株，在革兰氏阴性杆菌中，培养生长的大多数分离株是 （22.4%）。在21株分离株中，9例[9/21（42%）]检测到耐甲氧西林，这是一个值得关注的问题。因此，当下需要进行适当的培训并应用抗菌药物管理，以便临床医生能够尽早开始针对性治疗。
