Mann S C, Caroff S N, Bleier H R, Welz W K, Kling M A, Hayashida M
Am J Psychiatry. 1986 Nov;143(11):1374-81. doi: 10.1176/ajp.143.11.1374.
Lethal catatonia, a life-threatening febrile neuropsychiatric disorder, was widely reported in this country and abroad before the introduction of modern psychopharmacologic treatments. A comprehensive review of the world literature indicates that although the prevalence of lethal catatonia may have declined, it continues to occur, now reported primarily in the foreign literature. Lack of recognition probably accounts for the scarcity of recent American reports. Furthermore, lethal catatonia is a syndrome rather than a specific disease and may develop in association with both functional and organic illnesses. Familiarity with the clinical features and varied etiologies is essential for effective management of this catastrophic reaction.
致死性紧张症是一种危及生命的发热性神经精神障碍，在现代精神药物治疗出现之前，国内外对此有广泛报道。对世界文献的全面回顾表明，尽管致死性紧张症的患病率可能有所下降，但仍有发生，目前主要在国外文献中有报道。认识不足可能是近期美国相关报告较少的原因。此外，致死性紧张症是一种综合征而非特定疾病，可能与功能性和器质性疾病相关。熟悉其临床特征和多种病因对于有效管理这种灾难性反应至关重要。
