Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, Massachusetts, U.S.A.
Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, Massachusetts, U.S.A.
Laryngoscope. 2024 Apr;134(4):1597-1602. doi: 10.1002/lary.31082. Epub 2023 Sep 29.
The COVID-19 pandemic affected the epidemiology of several diseases. This study aims to compare the incidence of surgically treated odontogenic sinusitis (ODS) before and during the COVID-19 pandemic and identify unique features.
A retrospective chart review of patients who underwent at least maxillary antrostomy at a tertiary referral center was performed. The patients were divided into two cohorts: "pre-COVID" (March 2018 to February 2020) and "COVID" (March 2020 to February 2022). Data on demographics, comorbidities, and treatment interventions were collected and analyzed.
Of the 734 patients who underwent maxillary antrostomy, 370 (50.4%) were operated on during the COVID period, with a mean age of 53.1 ± 15.7 years. ODS was found as the etiology of 22 (6%) and 45 (12.2%) of the pre-COVID and COVID cases, respectively (p = 0.006). Although no difference was found in the incidence of diabetes (p = 0.9) or obesity (p = 0.7) between groups, a trend toward higher incidence of immunosuppression was found in the pre-COVID patients (18.2% vs. 0%, p = 0.06). A higher incidence of sphenoid sinus involvement (31.8% vs. 8.9%, p < 0.05) was identified in the pre-COVID group; however, no differences in ethmoid (86.4% vs. 86.7%, p = 0.999) or frontal sinus involvement (54.5% vs. 37.8%, p = 0.3) were found between the groups.
There was an increase in the incidence of ODS during the first 2 years of the COVID-19 pandemic compared to the 2 years prior. Similar clinical characteristics were found in both groups. Future studies focusing on specific etiologies to explain ODS preponderance may help determine optimal treatment and prevention strategies.
3 Laryngoscope, 134:1597-1602, 2024.
COVID-19 大流行影响了几种疾病的流行病学。本研究旨在比较 COVID-19 大流行前后手术治疗牙源性鼻窦炎（ODS）的发病率，并确定其独特特征。
对一家三级转诊中心行至少上颌窦切开术的患者进行回顾性图表审查。患者分为两组：“COVID 前”（2018 年 3 月至 2020 年 2 月）和“COVID”（2020 年 3 月至 2022 年 2 月）。收集并分析患者的人口统计学、合并症和治疗干预数据。
在 734 例行上颌窦切开术的患者中，370 例（50.4%）在 COVID 期间接受手术治疗，平均年龄为 53.1±15.7 岁。COVID 前和 COVID 病例中，ODS 分别为 22（6%）和 45 例（12.2%）的病因（p=0.006）。尽管两组之间糖尿病（p=0.9）或肥胖（p=0.7）的发病率无差异，但 COVID 前患者的免疫抑制发生率呈上升趋势（18.2%比 0%，p=0.06）。COVID 前组蝶窦受累发生率较高（31.8%比 8.9%，p<0.05）；然而，两组筛窦（86.4%比 86.7%，p=0.999）或额窦受累（54.5%比 37.8%，p=0.3）无差异。
与 COVID-19 大流行前的 2 年相比，COVID-19 大流行的头 2 年 ODS 的发病率有所增加。两组的临床特征相似。未来的研究集中在特定的病因上，以解释 ODS 的优势，可能有助于确定最佳的治疗和预防策略。
3 级喉镜，134：1597-1602，2024。
