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改良Caldwell-Luc入路治疗无需功能性鼻内镜鼻窦手术的牙源性上颌窦炎:一项回顾性研究

The Modified Caldwell-Luc Approach for Treating Odontogenic Maxillary Sinusitis Without Need for Functional Endoscopic Sinus Surgery: A Retrospective Study.

作者信息

Nashef Aysar, Joachim Michael V, Liubin Nina, Abdel Raziq Murad, Abu El-Naaj Imad, Laviv Amir

机构信息

Department of Oral and Maxillofacial Surgery, Meir Medical Center, Affiliated with the Faculty of Medicine, Tel-Aviv University, Kfar-Saba, Israel.

Unit of Oral and Maxillofacial Surgery, Shamir (Assaf ha-Rofeh) Medical Center, Tzrifin, Israel; Faculty of Medicine, Goldschleger School of Dentistry, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Oral Maxillofac Surg. 2025 Feb;83(2):199-207. doi: 10.1016/j.joms.2024.09.006. Epub 2024 Oct 4.

Abstract

BACKGROUND

Odontogenic maxillary sinusitis is a common inflammatory condition resulting from the violation of the Schneiderian membrane by conditions arising from the dentoalveolar unit, which includes teeth, their supporting structures, and adjacent tissues. This study aims to evaluate a modified surgical approach for treating this condition.

PURPOSE

The purpose of this study is to measure the frequency of retreatment of maxillary sinusitis of odontogenic origin following treatment with a modified Caldwell-Luc approach, which involves accessing the maxillary sinus through the canine fossa without creating a counter-opening in the inferior nasal meatus.

STUDY DESIGN, SETTING, SAMPLE: This retrospective cohort study included 82 cases (83 sinuses) with odontogenic sinusitis treated surgically with the modified Caldwell-Luc technique at the Department of Oral and Maxillofacial Surgery, Poriya Medical Center, between 2014 and 2021. Patients with nonodontogenic sinusitis were excluded.

PREDICTOR VARIABLE

Anatomic findings defined as the presence or absence of ostiomeatal complex abnormalities and oroantral communication, as identified through clinical examination and computed tomography imaging.

MAIN OUTCOME VARIABLES

The need for retreatment, defined as the requirement for functional endoscopic sinus surgery (FESS) due to persistent signs and symptoms of maxillary sinusitis after the modified Caldwell-Luc procedure, including facial pain/pressure, nasal congestion, purulent nasal discharge, or radiographic evidence of persistent sinus opacification on computed tomography scan, lasting more than 4 weeks despite appropriate medical management.

COVARIATES

Covariates included demographic data (age, sex [male/female as identified at birth]), smoking status, etiologies of odontogenic sinusitis, and surgical conditions.

ANALYSES

Descriptive statistics, Cox proportional hazards regression was used to compute hazard ratios (HRs). Kaplan-Meier survival analysis was performed to estimate the probability of remaining FESS-free over time. The level of statistical significance was set at P < .05.

RESULTS

The sample was composed of 82 patients (83 sinuses) with a mean age of 52.3 years (SD 13.5), and 47 (56.6%) were male. Dental implantation and sinus augmentation procedures were the most common etiologies of odontogenic sinusitis (50.6%). The median follow-up time was 6.03 months (interquartile range: 2.57 to 10.93 months). The incidence rate of FESS requirement was 2.64 per 100 person-months of follow-up. The FESS-free frequency was 89.2% (95% CI: 80.4 to 94.4%). The Kaplan-Meier analysis estimated the probability of remaining FESS-free at 12 months to be 89.1% (95% CI: 79.8 to 94.4%). Patients with ostiomeatal complex abnormalities had an HR of 2.25 (95% CI: 0.47 to 10.84, P = .31) for requiring FESS, while those with oroantral communication had an HR of 1.85 (95% CI: 0.46 to 7.39, P = .38).

CONCLUSION AND RELEVANCE

The modified Caldwell-Luc procedure was effective in treating the majority of odontogenic sinusitis cases. FESS may be necessary in a small percentage of cases with persistent symptoms. Further research is needed to identify predictors for FESS requirement. Of note, we recommend that oral and maxillofacial surgery surgeons review sinusitis cases with a FESS surgeon before performing the modified Caldwell-Luc procedure creating the opportunity for simultaneous or closely timed procedures when necessary.

摘要

背景

牙源性上颌窦炎是一种常见的炎症性疾病,由牙槽单位(包括牙齿、其支持结构和相邻组织)引发的情况侵犯施奈德膜所致。本研究旨在评估一种改良手术方法治疗该疾病的效果。

目的

本研究的目的是测量采用改良考德威尔 - 卢氏法治疗后牙源性上颌窦炎的再治疗频率,该方法是通过犬齿窝进入上颌窦,而不在下鼻道做对口开窗。

研究设计、设置、样本:这项回顾性队列研究纳入了2014年至2021年期间在波里亚医疗中心口腔颌面外科接受改良考德威尔 - 卢氏技术手术治疗的82例(83个鼻窦)牙源性鼻窦炎病例。排除非牙源性鼻窦炎患者。

预测变量

通过临床检查和计算机断层扫描成像确定的解剖学发现,定义为是否存在窦口鼻道复合体异常和口鼻窦交通。

主要结局变量

再治疗需求,定义为改良考德威尔 - 卢氏手术后因上颌窦炎持续的体征和症状而需要进行功能性内镜鼻窦手术(FESS),包括面部疼痛/压痛、鼻塞、脓性鼻分泌物,或计算机断层扫描显示鼻窦持续混浊的影像学证据,尽管进行了适当的药物治疗,但持续超过4周。

协变量

协变量包括人口统计学数据(年龄、性别[出生时确定的男性/女性])、吸烟状况、牙源性鼻窦炎的病因和手术情况。

分析

采用描述性统计,Cox比例风险回归用于计算风险比(HRs)。进行Kaplan - Meier生存分析以估计随时间保持无需FESS的概率。统计学显著性水平设定为P <.05。

结果

样本包括82例患者(83个鼻窦),平均年龄52.3岁(标准差13.5),47例(56.6%)为男性。牙种植和鼻窦增大手术是牙源性鼻窦炎最常见的病因(50.6%)。中位随访时间为6.03个月(四分位间距:2.57至10.93个月)。FESS需求的发生率为每100人 - 月随访2.64例。无需FESS的频率为89.2%(95%置信区间:80.4至94.4%)。Kaplan - Meier分析估计12个月时保持无需FESS的概率为89.1%(95%置信区间:79.8至94.4%)。窦口鼻道复合体异常的患者需要FESS的HR为2.25(95%置信区间:0.47至10.84,P = 0.31),而有口鼻窦交通的患者HR为1.85(95%置信区间:0.46至7.39,P = 0.38)。

结论及相关性

改良考德威尔 - 卢氏手术对大多数牙源性鼻窦炎病例有效。在一小部分有持续症状的病例中可能需要FESS。需要进一步研究以确定FESS需求的预测因素。值得注意的是,我们建议口腔颌面外科医生在进行改良考德威尔 - 卢氏手术前与FESS外科医生会诊鼻窦炎病例,以便在必要时为同时或紧密安排的手术创造机会。

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