Borodovsky Jacob T, Struble Cara A, Habib Mohammad I, Hasin Deborah S, Shmulewitz Dvora, Walsh Claire, Livne Ofir, Aharonovich Efrat, Budney Alan J
Center for Technology and Behavioral Health, Dartmouth Geisel School of Medicine, Lebanon, NH, Lebanon.
Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, Hanover, NH, USA.
Am J Drug Alcohol Abuse. 2023 Nov 2;49(6):733-745. doi: 10.1080/00952990.2023.2246635. Epub 2023 Dec 11.
Researchers need accurate measurements of cannabis consumption quantities to assess risks and benefits. Survey methods for measuring cannabis flower and concentrate quantities remain underdeveloped. We examined "grams" and "hits" units for measuring flower and concentrate quantities, and calculating milligrams of THC (mgTHC). Online survey participants ( = 2,381) reported preferred unit (hits grams), past-week hits grams for each product, and product %THC. Quantile regression compared mgTHC between unit-preference subgroups. Hits-based mgTHC calculations assumed a universal grams-per-hit ratio (GPHR). To examine individualized GPHRs, we tested a "two-item approach," which divided total grams by total hits, and "one-item approach," which divided 0.5 grams by responses to the question: [product] [administration method]?" Participants were primarily daily consumers (77%), 50% female sex, mean age 39.0 (SD 16.4), 85% White, 49% employed full-time. Compared to those who preferred the hits unit, those who preferred the grams unit reported consuming more hits grams, higher %THC products, and consequently, larger median mgTHC (flower-hits mgTHC: 32 vs. 91 (95%CI: 52-67); flower-grams mgTHC: 27 vs. 113 (95%CI: 73-95); concentrate-hits mgTHC: 29 vs. 59 (95%CI: 15-43); concentrate-grams mgTHC: 61 vs. 129 (95%CI: 43-94)). "Two-item" and "one-item" approach GPHRs were similar and frequently 50% larger or smaller than the universal GPHR. Allowing respondents to choose "hits" or "grams" when reporting cannabis quantities does not compromise mgTHC estimates. A low-burden, one-item approach yields individualized "hit sizes" that may improve mgTHC estimates.
研究人员需要准确测量大麻的消费量,以评估其风险和益处。用于测量大麻花和浓缩物数量的调查方法仍不发达。我们研究了用于测量花和浓缩物数量以及计算四氢大麻酚毫克数(mgTHC)的“克”和“次”单位。在线调查参与者(n = 2381)报告了首选单位(次/克)、每种产品过去一周的次/克用量以及产品的四氢大麻酚百分比(%THC)。分位数回归比较了单位偏好亚组之间的mgTHC。基于“次”的mgTHC计算假定了一个通用的每次用量克数比(GPHR)。为了检验个体化的GPHR,我们测试了“两项法”(将总克数除以总次数)和“一项法”(将0.5克除以对问题“[产品][给药方式]?”的回答)。参与者主要是每日使用者(77%),50%为女性,平均年龄39.0岁(标准差16.4),85%为白人,49%为全职工作。与那些更喜欢“次”单位的人相比,那些更喜欢“克”单位的人报告的次/克用量更多、产品的%THC更高,因此,mgTHC的中位数更大(花-次mgTHC:32对91(95%CI:52 - 67);花-克mgTHC:27对113(95%CI:73 - 95);浓缩物-次mgTHC:29对59(95%CI:15 - 43);浓缩物-克mgTHC:61对129(95%CI:43 - 94))。“两项法”和“一项法”的GPHR相似,且通常比通用GPHR大50%或小50%。允许受访者在报告大麻用量时选择“次”或“克”不会影响mgTHC的估计。一种低负担的一项法可得出个体化的“每次用量大小”,这可能会改善mgTHC的估计。