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通过柚子皮生物质炭从溶液中高效去除嘌呤化合物。

Efficient removal of purine compounds from solutions via biomass carbons derived from pomelo peel.

作者信息

Chen Dai Di, Li Qingxin, Wu Jin Chuan

机构信息

Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.

Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.

出版信息

J Biosci Bioeng. 2023 Nov;136(5):383-390. doi: 10.1016/j.jbiosc.2023.09.002. Epub 2023 Sep 27.

Abstract

The high purine diet could result in the increase of the level of blood uric acid, causing serious health problems such as hyperuricemia, gout, nephropathy and cardiovascular diseases. To find out a safe, cheap and super adsorption material for removing purines in stomach or pretreating high-purine beverages, we used different tissues of pomelo peel to prepare biomass carbon by drying, chemical modification and carbonization and then applied it to remove purine compounds in strong acidic solution, beer and soybean milk. The characteristic analysis of pomelo-peel-derived carbons (PPCs) indicated that the preparation methods significantly affected the structures and adsorption capacities of PPCs. Compared with the biomass carbon derived from bamboo, PPCs exhibited higher adsorption capabilities for purine compounds in strong acidic solution (adsorption rates > 99% in 15 min) and soybean milk (adsorption rates > 56% in 30 min) but slightly lower adsorption capabilities in beer (adsorption rates > 52% in 30 min). In addition, the adsorption capabilities of PPCs for purine compounds in beer and soybean milk were not obviously affected by temperatures. Therefore, PPCs are promising absorbents for applications in removing purine compounds from beverages to produce low-purine, healthier products for treating hyperuricemia. The strong adsorption capabilities of PPCs on purine compounds in strong acidic environment also provides a possibility of using the PPCs as food additives for removing purines in stomach for healthcare applications such as gout prevention after confirming their biosafety.

摘要

高嘌呤饮食会导致血尿酸水平升高,引发高尿酸血症、痛风、肾病和心血管疾病等严重健康问题。为了找到一种安全、廉价且具有超强吸附能力的材料来去除胃中的嘌呤或预处理高嘌呤饮料,我们利用柚子皮的不同组织,通过干燥、化学改性和碳化制备生物质炭,然后将其应用于去除强酸性溶液、啤酒和豆浆中的嘌呤化合物。柚子皮衍生炭(PPCs)的特性分析表明,制备方法显著影响了PPCs的结构和吸附能力。与竹材衍生的生物质炭相比,PPCs在强酸性溶液(15分钟内吸附率>99%)和豆浆(30分钟内吸附率>56%)中对嘌呤化合物表现出更高的吸附能力,但在啤酒中吸附能力略低(30分钟内吸附率>52%)。此外,PPCs对啤酒和豆浆中嘌呤化合物的吸附能力不受温度明显影响。因此,PPCs有望作为吸附剂应用于从饮料中去除嘌呤化合物,以生产低嘌呤、更健康的产品用于治疗高尿酸血症。PPCs在强酸性环境中对嘌呤化合物的强吸附能力,在确认其生物安全性后,也为将PPCs用作食品添加剂在胃中去除嘌呤以用于预防痛风等医疗保健应用提供了可能性。

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