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社会脆弱性与广泛手术人群中术后并发症的风险调整率升高有关。

Social vulnerability is associated with higher risk-adjusted rates of postoperative complications in a broad surgical population.

机构信息

Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA; Surgical Outcomes and Applied Research, University of Colorado School of Medicine, Aurora, CO, USA.

Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA.

出版信息

Am J Surg. 2024 Mar;229:26-33. doi: 10.1016/j.amjsurg.2023.09.028. Epub 2023 Sep 23.

Abstract

OBJECTIVE

The purpose of this study was to determine if an association between Social Vulnerability Index (SVI) and risk-adjusted complications exists in a broad spectrum of surgical patients.

SUMMARY BACKGROUND DATA

Growing evidence supports the impact of social circumstances on surgical outcomes. SVI is a neighborhood-based measure accounting for sociodemographic factors putting communities at risk.

METHODS

This was a multi-hospital, retrospective cohort study including a sample of patients within one healthcare system (2012-2017). Patient addresses were geocoded to determine census tract of residence and estimate SVI. Patients were grouped into low SVI (score<75) and high SVI (score≥75) cohorts. Perioperative variables and postoperative outcomes were tracked and compared using local ACS-NSQIP data. Multivariable logistic regression was performed to generate risk-adjusted odds ratios of postoperative complications in the high SVI cohort.

RESULTS

Overall, 31,224 patients from five hospitals were included. Patients with high SVI were more likely to be racial minorities, have 12/18 medical comorbidities, have high ASA class, be functionally dependent, be treated at academic hospitals, and undergo emergency operations (all p ​< ​0.05). Patients with high SVI had significantly higher rates of 30-day mortality, overall morbidity, respiratory, cardiac and infectious complications, urinary tract infections, postoperative bleeding, non-home discharge, and unplanned readmissions (all p ​< ​0.05). After risk-adjustment, only the associations between high SVI and mortality and unplanned readmission became non-significant.

CONCLUSIONS

High SVI was associated with multiple adverse outcomes even after risk adjustment for preoperative clinical factors. Targeted preventative interventions to mitigate risk of these specific complications should be considered in this high-risk population.

摘要

目的

本研究旨在确定社会脆弱性指数(SVI)与广泛手术患者风险调整后并发症之间是否存在关联。

背景资料摘要

越来越多的证据支持社会环境对手术结果的影响。SVI 是一种基于社区的衡量标准,用于衡量使社区面临风险的社会人口因素。

方法

这是一项多医院回顾性队列研究,包括一个医疗系统内的患者样本(2012-2017 年)。患者地址被地理编码以确定居住的普查区并估计 SVI。患者分为低 SVI(得分<75)和高 SVI(得分≥75)组。使用当地 ACS-NSQIP 数据跟踪和比较围手术期变量和术后结果。采用多变量逻辑回归生成高 SVI 组术后并发症的风险调整比值比。

结果

总体而言,来自五家医院的 31224 名患者被纳入研究。高 SVI 患者更有可能是少数族裔,有 12/18 种医疗合并症,ASA 分级较高,功能依赖,在学术医院接受治疗,并进行急诊手术(所有 p<0.05)。高 SVI 患者的 30 天死亡率、总发病率、呼吸系统、心脏和感染性并发症、尿路感染、术后出血、非家庭出院和计划外再入院率显著较高(所有 p<0.05)。风险调整后,仅高 SVI 与死亡率和计划外再入院之间的关联不再具有统计学意义。

结论

即使在对术前临床因素进行风险调整后,高 SVI 仍与多种不良结局相关。在这一高风险人群中,应考虑针对这些特定并发症的有针对性的预防干预措施。

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