Waxman K
Ann Emerg Med. 1986 Dec;15(12):1434-6. doi: 10.1016/s0196-0644(86)80937-4.
The transcutaneous oxygen (PtcO2) monitoring technique uses a Clark electrode applied noninvasively to the skin surface. To obtain PtcO2 values that respond rapidly to physiologic changes, the electrode is heated to 44 to 45 C. Since its introduction in 1972, the PtcO2 sensor has become standard for monitoring oxygenation of neonates in respiratory distress. However, when applied to critically ill or injured adult patients, PtcO2 values often are much lower than arterial oxygen (PaO2) values. The explanation for this is that PtcO2 reflects not only arterial oxygen tension, but also cardiac output and oxygen delivery. Thus, during low-cardiac-output shock states, PtcO2, values are low, even when PaO2 is normal or high. PtcO2 monitoring in adults thus is useful in assessing oxygen delivery. Comparison to an arterial blood gas can easily differentiate whether a low PtcO2 value might be due to hypoxia or to low cardiac output. Other noninvasive monitors (conjunctival oxygen, pulse oximeter, transcutaneous CO2, end-tidal CO2) also show promise. In the emergency department, PtcO2 monitoring is useful in assessing the presence and severity of shock and hypoxia and as a physiologic monitor for titrating resuscitation.
经皮氧分压(PtcO2)监测技术使用一个无创地应用于皮肤表面的克拉克电极。为了获得能快速响应生理变化的PtcO2值,电极被加热到44至45摄氏度。自1972年引入以来,PtcO2传感器已成为监测呼吸窘迫新生儿氧合情况的标准方法。然而,当应用于重症或受伤的成年患者时,PtcO2值往往远低于动脉血氧分压(PaO2)值。对此的解释是,PtcO2不仅反映动脉血氧张力,还反映心输出量和氧输送。因此,在低心输出量休克状态下,即使PaO2正常或升高,PtcO2值也会很低。因此,PtcO2监测在评估成年患者的氧输送方面很有用。与动脉血气分析进行比较可以很容易地区分低PtcO2值是由于缺氧还是低心输出量所致。其他无创监测方法(结膜氧分压、脉搏血氧饱和度仪、经皮二氧化碳分压、呼气末二氧化碳分压)也显示出前景。在急诊科,PtcO2监测对于评估休克和缺氧的存在及严重程度以及作为滴定复苏的生理监测手段很有用。