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Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.

作者信息

Rahmanzade Ramin, Pfaff Elke, Banan Rouzbeh, Sievers Philipp, Suwala Abigail K, Hinz Felix, Bogumil Henri, Cherkezov Asan, Kaan Aras Fuat, Schrimpf Daniel, Friedel Dennis, Göbel Kirsten, Keller Felix, Saenz-Sardà Xavier, Lossos Alexander, Sill Martin, Witt Olaf, Sakowitz Oliver W, Korshunov Andrey, Reuss David E, Etminan Nima, Unterberg Andreas, Ratliff Miriam, Herold-Mende Christel, Wick Wolfgang, Pfister Stefan M, von Deimling Andreas, Jones David T W, Sahm Felix

机构信息

Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

出版信息

Acta Neuropathol. 2023 Dec;146(6):853-856. doi: 10.1007/s00401-023-02638-1. Epub 2023 Sep 30.

DOI:10.1007/s00401-023-02638-1
PMID:37776353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10627898/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5500/10627898/72d677db701b/401_2023_2638_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5500/10627898/72d677db701b/401_2023_2638_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5500/10627898/72d677db701b/401_2023_2638_Fig1_HTML.jpg

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Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study.松果体实质肿瘤的临床和分子异质性：一项共识研究。
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本文引用的文献

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Survival and associated predictors for patients with pineoblastoma or pineal parenchymal tumors of intermediate differentiation older than 3 years: Insights from the National Cancer Database.3岁以上松果体母细胞瘤或间变性松果体实质肿瘤患者的生存情况及相关预测因素：来自美国国立癌症数据库的见解
Neurooncol Adv. 2022 Apr 17;4(1):vdac057. doi: 10.1093/noajnl/vdac057. eCollection 2022 Jan-Dec.
2
Prognosticating survival of pineal parenchymal tumors of intermediate differentiation (PPTID) by grade.按级别预测中间分化的松果体实质肿瘤（PPTID）的生存率。
J Neurooncol. 2021 Nov;155(2):165-172. doi: 10.1007/s11060-021-03863-y. Epub 2021 Oct 4.
3
理解与管理中间分化型松果体实质肿瘤：从病理学到辅助治疗的深入探索
J Clin Med. 2024 Feb 23;13(5):1266. doi: 10.3390/jcm13051266.
4
Reply: pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion.回复：中间分化型松果体实质肿瘤：需要严格定义以避免混淆。
Acta Neuropathol. 2024 Feb 10;147(1):35. doi: 10.1007/s00401-024-02685-2.
5
Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on 'Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics'.中间分化型松果体实质肿瘤：需要严格定义以避免混淆。对“遗传学和表观遗传学分析确定了中间分化型松果体实质肿瘤（PPTID）的两个亚组，具有不同的分子、组织学和临床特征”的科学评论
Acta Neuropathol. 2024 Feb 10;147(1):34. doi: 10.1007/s00401-024-02684-3.
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study.
松果体实质肿瘤的临床和分子异质性：一项共识研究。
Acta Neuropathol. 2021 May;141(5):771-785. doi: 10.1007/s00401-021-02284-5. Epub 2021 Feb 22.
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Neuro Oncol. 2017 Jan;19(1):78-88. doi: 10.1093/neuonc/now105. Epub 2016 Jun 9.
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Neuropathol Appl Neurobiol. 2012 Feb;38(1):87-94. doi: 10.1111/j.1365-2990.2011.01202.x.
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Parenchymal pineal tumors: a clinicopathological study of 76 cases.松果体实质肿瘤：76例临床病理研究
Int J Radiat Oncol Biol Phys. 2000 Mar 1;46(4):959-68. doi: 10.1016/s0360-3016(99)00389-2.
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Brain Pathol. 2000 Jan;10(1):49-60. doi: 10.1111/j.1750-3639.2000.tb00242.x.