Faysal M R, Akter T, Hossain M S, Begum S, Banu M, Sarkar S, Krishna S P, Sultana I, Hoque M R
Dr Mohammad Robin Faysal, Assistant Professor, Department of Biochemistry, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Mymensingh Med J. 2023 Oct;32(4):992-997.
A major global public health concern is the prevalence of diabetes mellitus, especially in developing countries like Bangladesh. While still battling communicable diseases, Bangladesh is already inundated with non-communicable diseases. Type 2 diabetes has been found in almost 90.0% of all instances of diabetes. The main risk factors for type 2 diabetes are an excessively caloric diet, advanced age, sedentary behavior and obesity. Along with preexisting risk factors, many micro-nutrients have been related to a rise in the incidence of diabetes. The study's objective was to measure and contrast the zinc levels in serum between individuals with type 2 diabetes mellitus and healthy controls. This cross-sectional study was conducted from July 2018 to June 2019 at the Mymensingh Medical College, Mymensingh, Bangladesh. Based on inclusion and exclusion criteria, the subjects were chosen using a purposeful (non-random) sample method. In total, 100 people participated in this study. They were divided into two groups: 50 individuals who had been diagnosed with type 2 diabetes mellitus were chosen as cases and 50 individuals who appeared to be in generally excellent health were chosen as controls. For the analytical aims of this investigation, serum zinc levels were examined. All values were expressed as the mean SD. The statistical analyses were carried out using the Windows program statistics package for social science (SPSS). The statistical significance of the difference between the case and control groups was evaluated using the Student's unpaired 't' test. A thorough research revealed that type 2 diabetes mellitus patients had significantly lower mean serum zinc levels than healthy controls (case group was 110.96±13.60 and control group 130.18±9.95μg/dl). Cross-sectional research was used in this study. The current study's findings showed that type 2 diabetes mellitus patients had dramatically changed serum zinc levels. The study's hypothesis was verified as a result.
糖尿病的流行是一个重大的全球公共卫生问题，尤其是在孟加拉国等发展中国家。在仍在与传染病作斗争的同时，孟加拉国已经被非传染性疾病所淹没。在所有糖尿病病例中，2型糖尿病占近90.0%。2型糖尿病的主要风险因素是高热量饮食、高龄、久坐不动的行为和肥胖。除了先前存在的风险因素外，许多微量营养素也与糖尿病发病率的上升有关。该研究的目的是测量和对比2型糖尿病患者与健康对照组血清中的锌水平。这项横断面研究于2018年7月至2019年6月在孟加拉国迈门辛医学院进行。根据纳入和排除标准，采用有目的（非随机）抽样方法选择研究对象。共有100人参与了这项研究。他们被分为两组：50名被诊断为2型糖尿病的个体被选为病例组，50名看起来总体健康状况良好的个体被选为对照组。为了实现本研究的分析目标，对血清锌水平进行了检测。所有数值均表示为均值±标准差。使用社会科学统计软件包（SPSS）的Windows程序进行统计分析。采用学生氏非配对“t”检验评估病例组和对照组之间差异的统计学显著性。一项全面的研究表明，2型糖尿病患者的平均血清锌水平显著低于健康对照组（病例组为110.96±13.60，对照组为130.18±9.95μg/dl）。本研究采用横断面研究方法。当前研究结果表明，2型糖尿病患者的血清锌水平发生了显著变化。研究假设因此得到验证。
