COVID-19 老年患者接受功能性电刺激对肌肉质量、疲劳和生活质量的影响：一项随机临床试验研究。

Effect of Functional Electrical Stimulation on Muscle Mass, Fatigue, and Quality of Life in Older Patients With COVID-19: A Randomized Clinical Trial Study.

机构信息

Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.

出版信息

J Manipulative Physiol Ther. 2023 Feb;46(2):65-75. doi: 10.1016/j.jmpt.2023.06.004. Epub 2023 Sep 29.

DOI:10.1016/j.jmpt.2023.06.004

PMID:37777938

Abstract

OBJECTIVE

This study aimed to evaluate the effects of functional electrical stimulation (FES) on muscle strength, fatigue, muscle mass, and quality of life (QoL) in older patients with COVID-19.

METHODS

Older patients with COVID-19 were randomly divided into the following 2 groups: real FES (intervention group, n = 20) and sham FES (control group, n = 20). These patients received FES concurrent with the voluntary contraction of muscles for 10 consecutive sessions. Ultrasound imaging, pressure biofeedback, Chalder fatigue scale, and QoL were utilized to measure muscle mass, muscle strength, chronic fatigue, and QoL, respectively. Evaluations were performed at the beginning, immediately, and 1 month after the end of intervention.

RESULTS

All variables showed statistically significant improvement immediately and 1 month after the intervention in the real FES group (P < .05). However, the tibialis anterior muscle mass and fatigue significantly improved immediately after the intervention in the sham FES group. However, the tibialis anterior and rectus femoris muscles strength and rectus femoris muscle mass were not significantly changed immediately and 1 month after the intervention (P > .05). There were significant differences in muscle mass, physical fatigue, muscle strength, and QoL between groups with more efficacy of real FES (P < .05).

CONCLUSION

For this sample of patients, FES improved fatigue, muscle strength, muscle mass, and QoL in older adults with COVID-19.

摘要

目的

本研究旨在评估功能性电刺激（FES）对 COVID-19 老年患者肌肉力量、疲劳、肌肉质量和生活质量（QoL）的影响。

方法

将 COVID-19 老年患者随机分为真 FES（干预组，n=20）和假 FES（对照组，n=20）两组。这些患者接受 FES 与肌肉自愿收缩相结合的连续 10 次治疗。使用超声成像、压力生物反馈、Chalder 疲劳量表和 QoL 分别测量肌肉质量、肌肉力量、慢性疲劳和 QoL。在干预开始时、干预结束时即刻和 1 个月后进行评估。

结果

在真 FES 组，所有变量在干预结束时即刻和 1 个月后均显示出统计学上的显著改善（P<0.05）。然而，假 FES 组仅在干预结束时即刻观察到胫骨前肌质量和疲劳显著改善。然而，胫骨前肌和股直肌力量以及股直肌质量在干预结束时即刻和 1 个月后均未发生显著变化（P>0.05）。两组间在肌肉质量、躯体疲劳、肌肉力量和 QoL 方面存在显著差异，真 FES 组的疗效更显著（P<0.05）。