Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; RPA Institute of Academic Surgery (IAS), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; Faculty of Medicine and Health, Central Clinical School, The University of Sydney, Sydney, New South Wales, Australia.
Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; RPA Institute of Academic Surgery (IAS), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; Faculty of Medicine and Health, Central Clinical School, The University of Sydney, Sydney, New South Wales, Australia.
Urology. 2023 Dec;182:136-142. doi: 10.1016/j.urology.2023.09.019. Epub 2023 Sep 29.
To explore the association between preoperative mental health status and surgical outcomes following robotic-assisted radical prostatectomy (RARP).
This cohort study included consecutive patients undergoing RARP surgery for prostate cancer between October 2016 and May 2022 at a major public hospital in Sydney, Australia. The primary outcome was preoperative self-reported mental health status measured using the mental component score from the Short Form 36 survey. Other variables included patients' characteristics, surgical outcomes, postoperative quality of life, pain and decision regret. Data were analysed using linear regression analysis.
A total of 266 men underwent RARP during the studied period. Of these, 242 patients (91%) completed the preoperative survey and were analyzed. Poorer preoperative mental health had significant univariate associations with younger age (P = .025), reduced access to economic resources (P = .043), diagnosis of a mental illness (P = .033), poorer mental health at 6 weeks and 6 months postoperatively (both P <.001), greater pain (P = .001), and higher decision regret (P = .001) 6 weeks following surgery. In the multivariate analysis, poorer preoperative mental health status was associated with younger age (P = .028) and poorer mental health at 6 weeks (P <.001) and 6 months (P = .025) postoperatively.
For patients undergoing RARP, poor preoperative mental health status was associated with younger age and poorer postoperative mental health. Future studies should investigate if targeted preoperative psychological interventions would improve postoperative mental health outcomes, specifically in younger men undergoing RARP.
探讨机器人辅助前列腺根治性切除术(RARP)前心理健康状况与手术结果的关系。
本队列研究纳入了 2016 年 10 月至 2022 年 5 月期间在澳大利亚悉尼一家主要公立医院接受 RARP 手术治疗前列腺癌的连续患者。主要结果是使用 36 项简短健康调查的心理成分评分来衡量术前自我报告的心理健康状况。其他变量包括患者特征、手术结果、术后生活质量、疼痛和决策后悔。数据分析采用线性回归分析。
在研究期间,共有 266 名男性接受了 RARP。其中,242 名(91%)患者完成了术前调查并进行了分析。术前心理健康状况较差与年龄较小(P=0.025)、经济资源获取减少(P=0.043)、精神疾病诊断(P=0.033)、术后 6 周和 6 个月心理健康状况较差(均 P<.001)、疼痛更大(P=0.001)和手术 6 周后决策后悔更高(P=0.001)存在显著的单变量相关性。在多变量分析中,术前心理健康状况较差与年龄较小(P=0.028)以及术后 6 周(P<.001)和 6 个月(P=0.025)心理健康状况较差相关。
对于接受 RARP 的患者,术前心理健康状况较差与年龄较小以及术后心理健康状况较差相关。未来的研究应探讨是否针对术前的心理干预措施可以改善术后心理健康结果,特别是在接受 RARP 的年轻男性中。