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探索机器人辅助根治性前列腺切除术后患者的决策后悔:一项前瞻性队列研究。

Exploring patient decision regret following robot-assisted radical prostatectomy: a prospective cohort study.

作者信息

Hirst Nicholas, Chow Aidan, Treacy Patrick-Julien, Bird Jacob, Alexander Kate, Karunaratne Sascha, Steffens Daniel, Chan Lewis, Leslie Scott, Thanigasalam Ruban

机构信息

Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box M157, Sydney, NSW, 2050, Australia.

Faculty of Medicine and Health, Central Clinical School, The University of Sydney, Sydney, NSW, Australia.

出版信息

J Robot Surg. 2025 Aug 15;19(1):486. doi: 10.1007/s11701-025-02665-y.

Abstract

INTRODUCTION

There exists a paucity of evidence within Australia relating to rates and predictors of postoperative decision regret in patients undergoing Robot-Assisted Radical Prostatectomy. This study reports rates of decision regret up to 1 year postoperatively and aims to identify predictors of postoperative decision regret. The secondary aim is to test an association between participant's decision regret with surgical, functional and quality of life outcomes.

METHODS

This study included patients undergoing Robot-Assisted Radical Prostatectomy between 2016 and 2023 at a major tertiary hospital in Sydney. Regret was measured using the Decision Regret Scale, with scores > 25 indicating high level of regret. Associations between decision regret and surgical, functional and quality-of-life outcomes were explored using univariate and multivariate logistic regressions.

RESULTS

In total, 242 participants were included. Mean decision regret scores were similar at 6 weeks (20.3 ± 20.6), 3 months (22.5 ± 22.6), and 1 year (21.5 ± 22.5) postoperatively. Most participants' decision regret remained within their high or low regret group across all three postoperative timepoints. Participant reported measures of greater pain, urinary, sexual, bowel, hormonal symptoms and worse quality of life were all significantly different between high and low regret groups. Poor preoperative mental health was significantly associated with higher 6 week postoperative decision regret, suggesting a potential predictive relationship.

CONCLUSIONS

Most participants reporting high or low decision regret following Robot-Assisted Radical Prostatectomy maintain this regret up to 1 year postoperatively. Future studies should corroborate and investigate interventions to reduce participant decision regret.

摘要

引言

在澳大利亚,关于接受机器人辅助根治性前列腺切除术的患者术后决策后悔率及预测因素的证据很少。本研究报告了术后1年内的决策后悔率,并旨在确定术后决策后悔的预测因素。次要目的是检验参与者的决策后悔与手术、功能及生活质量结果之间的关联。

方法

本研究纳入了2016年至2023年期间在悉尼一家大型三级医院接受机器人辅助根治性前列腺切除术的患者。使用决策后悔量表测量后悔程度,得分>25表明后悔程度高。使用单因素和多因素逻辑回归探讨决策后悔与手术、功能及生活质量结果之间的关联。

结果

总共纳入了242名参与者。术后6周(20.3±20.6)、3个月(22.5±22.6)和1年(21.5±22.5)时的平均决策后悔得分相似。在所有三个术后时间点,大多数参与者的决策后悔仍处于高后悔组或低后悔组。参与者报告的疼痛、泌尿、性、肠道、激素症状较重以及生活质量较差的指标在高后悔组和低后悔组之间均有显著差异。术前心理健康状况较差与术后6周决策后悔程度较高显著相关,提示可能存在预测关系。

结论

大多数在机器人辅助根治性前列腺切除术后报告高或低决策后悔的参与者在术后1年内仍保持这种后悔。未来的研究应证实并调查减少参与者决策后悔的干预措施。

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