分离和鉴定慢病毒 Ib 亚株及其在愠怒小鼠中的发病机制。
Isolation and characterization of Akabane virus Ib substrain and its pathogenesis in sulking mice.
机构信息
State Key Laboratory of Reproductive Regulation & Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, 010070, China.
CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
出版信息
Virol Sin. 2023 Dec;38(6):966-970. doi: 10.1016/j.virs.2023.09.006. Epub 2023 Sep 29.
• Akabane virus sub-lineage genogroup Ib was identified and isolated in China for the first time. • The suckling mice showed clinical symptoms after intracerebrally infected with LK07 strain. • Viral antigen was detected in brain of mice infected with LK07 strain via IC, IP and SC routes.
• 在中国首次鉴定并分离出阿卡斑病毒亚谱系基因 Ib 。 • LK07 株感染乳鼠后出现临床症状。 • 通过脑内、腹腔和皮下感染途径，在感染 LK07 株的小鼠脑组织中检测到病毒抗原。
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