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中国首例山羊赤羽病病毒的分离与基因分析。

Isolation, genetic analysis of the first Akabane virus from goat in China.

作者信息

Tang Hai-Bo, Ren Pengfei, Qin Shuying, Lin Jun, Bai Anbin, Qin Shaomin, Chen Fenglian, Liu Jinfeng, Wu Jianmin

机构信息

Guangxi Veterinary Research Institute, Nanning 530001, China.

College of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China.

出版信息

J Vet Med Sci. 2019 Oct 18;81(10):1445-1449. doi: 10.1292/jvms.18-0602. Epub 2019 Aug 5.

DOI:10.1292/jvms.18-0602
PMID:31378772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6863719/
Abstract

Akabane virus (AKAV) is an important insect-borne virus belonging to the genus Orthobunyavirus, the Peribunyaviridae family. An AKAV defined as GXDH 01 here, was isolated for the first time from blood from a sentinel goat in China in 2016, and its full-length open reading frames (ORFs) were sequenced in this study. Sequence analysis suggested that the isolate GXDH 01 probably had undergone a reassortment incident and acquired L segments from other strain originating from an attenuated vaccine, such as OBE-1. This study aims to provide more understanding as to the origin and epidemiology of AKAV in China.

摘要

赤羽病毒(AKAV)是一种重要的虫媒病毒,属于正布尼亚病毒属,布尼亚病毒科。这里定义为GXDH 01的一株赤羽病毒于2016年首次从中国一只哨兵山羊的血液中分离出来,本研究对其全长开放阅读框(ORF)进行了测序。序列分析表明,分离株GXDH 01可能经历了一次重配事件,并从其他源自减毒疫苗(如OBE-1)的毒株获得了L片段。本研究旨在更深入了解中国赤羽病毒的起源和流行病学情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc53/6863719/46336a339bab/jvms-81-1445-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc53/6863719/46336a339bab/jvms-81-1445-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc53/6863719/46336a339bab/jvms-81-1445-g001.jpg

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Vet Microbiol. 2017 Aug;207:7-12. doi: 10.1016/j.vetmic.2017.05.014. Epub 2017 May 20.
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Characterization of Akabane virus from domestic bamboo rat, Southern China.
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