Wu Jialu, Yan Zhe, Li Bo, Yu Xijie, Huang Hui
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, PR China.
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, PR China.
Clin Ther. 2023 Dec;45(12):1293-1296. doi: 10.1016/j.clinthera.2023.09.012. Epub 2023 Sep 29.
This is a case report of a patient experiencing hyponatremia who was ultimately diagnosed with pituitary apoplexy-associated cerebral salt wasting syndrome (CSWS).
Laboratory tests, clinical evaluations, and magnetic resonance imaging were performed by specialists.
The patient presented with severe headache, thirst, and polyuria. Results of laboratory tests indicated hyponatremia, decreased plasma osmolality, and elevated urine osmolality. Fluid restriction worsened the situation, and normal saline treatment helped return serum sodium and chloride levels to normal. Pituitary apoplexy-associated CSWS was finally considered.
Pituitary apoplexy is a rare but reasonable etiology for CSWS with hyponatremia. Saline therapy is usually effective.
本文报告一例最终被诊断为垂体卒中相关性脑性盐耗综合征（CSWS）的低钠血症患者。
由专家进行实验室检查、临床评估及磁共振成像。
患者出现严重头痛、口渴及多尿。实验室检查结果显示低钠血症、血浆渗透压降低及尿渗透压升高。限水使情况恶化，生理盐水治疗有助于血清钠和氯水平恢复正常。最终考虑为垂体卒中相关性CSWS。
垂体卒中是CSWS伴低钠血症的一种罕见但合理的病因。生理盐水治疗通常有效。
