Department of Pulmology, Soka Municipal Hospital, Japan.
Intern Med. 2023 Dec 1;62(23):3515-3518. doi: 10.2169/internalmedicine.1790-23. Epub 2023 Sep 29.
An 85-year-old woman was diagnosed with coronavirus disease 2019 (COVID-19). The patient was treated with dexamethasone, and the infection was cured. She later developed a low-grade fever and fell unconscious. Positivity for herpes simplex virus deoxyribonucleic acid polymerase chain reaction (HSV-DNA PCR) was detected in the cerebrospinal fluid, so she was diagnosed with HSV encephalitis. The patient was treated with antiviral drugs and recovered from the HSV encephalitis. This case suggests that, in patients with COVID-19 and disorders of consciousness, the possibility of HSV encephalitis should be considered along with COVID-19 encephalitis.
一位 85 岁女性被诊断患有 2019 年冠状病毒病(COVID-19)。该患者接受了地塞米松治疗,感染得到治愈。后来,她出现低热并失去意识。在脑脊液中检测到单纯疱疹病毒脱氧核糖核酸聚合酶链反应(HSV-DNA PCR)阳性,因此被诊断为单纯疱疹病毒脑炎。患者接受了抗病毒药物治疗,HSV 脑炎得以康复。该病例提示,对于 COVID-19 患者且意识障碍者,除 COVID-19 脑炎外,还应考虑单纯疱疹病毒脑炎的可能性。