度普利尤单抗治疗细胞毒性T淋巴细胞抗原4功能不全所致严重皮肤病的疗效：2型炎症起了什么作用？
Efficacy of dupilumab for the treatment of severe skin disease in cytotoxic T lymphocyte antigen-4 insufficiency: A role of type 2 inflammation?
作者信息
Arruda L Karla, Cordeiro Daniel L, Langer Sarah S, Koenigham-Santos Marcel, Calado Rodrigo T, Dias Marina M, Anhesini Leonardo R, Oliveira João Bosco, Grimbacher Bodo, Ferriani Mariana P L
机构信息
Department of Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
出版信息
J Allergy Clin Immunol Glob. 2022 Sep 22;2(1):114-117. doi: 10.1016/j.jacig.2022.08.004. eCollection 2023 Feb.
We report on the successful treatment of a severe, recalcitrant dermatitis caused by CTLA-4 insufficiency with dupilumab, raising the possibility of a role of type 2 immunity in clinical conditions associated with CTLA-4 insufficiency.
我们报告了用度普利尤单抗成功治疗由CTLA-4功能不全引起的严重、顽固性皮炎的病例，这增加了2型免疫在与CTLA-4功能不全相关的临床病症中发挥作用的可能性。
Zotero 插件