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一名牛奶过敏儿童发生疫苗诱导的过敏反应:水合乳糖是罪魁祸首。

Vaccine-induced anaphylaxis in a child with cow's milk allergy: Lactose hydrate was the culprit.

作者信息

Yoshino Shoko, Hiraguchi Yukiko, Tatekawa Mari, Shingaki Tomoya, Kumagai Yusuke, Ebishima Yuko, Kiyomasu Takahiro, Owa Kenji, Suehiro Yutaka, Nagao Mizuho, Fujisawa Takao

机构信息

Center of Allergy and Clinical Immunology, Department of Pediatrics, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.

Department of Pediatrics, Kobe City Hospital Organization Kobe City Medical Center West Hospital, Kobe, Japan.

出版信息

J Allergy Clin Immunol Glob. 2022 Mar 9;1(2):87-89. doi: 10.1016/j.jacig.2022.01.003. eCollection 2022 May.

DOI:10.1016/j.jacig.2022.01.003
PMID:37780587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10509965/
Abstract

Lactose hydrate was the cause of vaccine-induced anaphylaxis in a child with severe milk allergy. Although the amount of milk protein in lactose-containing vaccines is extremely small, physicians administering such a vaccine must be prepared for the potential risk of severe milk allergy.

摘要

水合乳糖是一名患有严重牛奶过敏的儿童疫苗诱导过敏反应的病因。尽管含乳糖疫苗中的牛奶蛋白含量极少,但接种此类疫苗的医生必须对严重牛奶过敏的潜在风险有所准备。

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Vaccine-induced anaphylaxis in a child with cow's milk allergy: Lactose hydrate was the culprit.一名牛奶过敏儿童发生疫苗诱导的过敏反应:水合乳糖是罪魁祸首。
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本文引用的文献

1
Allergic reactions to cow's milk proteins in medications in childhood.儿童期药物中牛奶蛋白引起的过敏反应。
Acta Biomed. 2019 Jan 29;90(3-S):91-93. doi: 10.23750/abm.v90i3-S.8169.
2
Highly increased levels of IgE antibodies to vaccine components in children with influenza vaccine-associated anaphylaxis.在流感疫苗相关过敏反应的儿童中,针对疫苗成分的 IgE 抗体水平显著升高。
J Allergy Clin Immunol. 2016 Mar;137(3):861-7. doi: 10.1016/j.jaci.2015.08.001. Epub 2015 Sep 11.
3
Hypersensitivity reaction after inhalation of a lactose-containing dry powder inhaler.
吸入含乳糖的干粉吸入器后的超敏反应。
J Pediatr Pharmacol Ther. 2014 Jul;19(3):206-11. doi: 10.5863/1551-6776-19.3.206.
4
Hypersensitivity reactions to the Sabin vaccine in children with cow's milk allergy.小儿牛奶过敏对沙宾疫苗的过敏反应。
Clin Exp Allergy. 2013 Feb;43(2):249-54. doi: 10.1111/cea.12059.
5
[Studies on the food allergenic proteins contained in pharmaceutical excipients].[药用辅料中所含食物过敏原蛋白的研究]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2012(130):58-65.
6
Anaphylaxis to diphtheria, tetanus, and pertussis vaccines among children with cow's milk allergy.牛奶过敏儿童对白喉、破伤风和百日咳疫苗的过敏反应。
J Allergy Clin Immunol. 2011 Jul;128(1):215-8. doi: 10.1016/j.jaci.2011.04.046. Epub 2011 May 31.
7
Vaccine hypersensitivity--update and overview.疫苗过敏反应——更新与概述。
Swiss Med Wkly. 2010 May 1;140(17-18):238-46. doi: 10.4414/smw.2010.12980.
8
Antigen-induced expression of CD203c on basophils predicts IgE-mediated wheat allergy.抗原诱导的嗜碱性粒细胞上CD203c的表达可预测IgE介导的小麦过敏。
Allergol Int. 2009 Jun;58(2):193-9. doi: 10.2332/allergolint.08-OA-0023. Epub 2009 Feb 25.