Tsuzuki Yumi, Ishida Yusuke, Tomino Mikiko
Department of Anesthesiology Tokyo Medical University Tokyo Japan.
Clin Case Rep. 2023 Sep 27;11(10):e7988. doi: 10.1002/ccr3.7988. eCollection 2023 Oct.
Disorder of consciousness can lead to irreversible sequelae without proper intervention. Consequently, early diagnosis and treatment are of paramount importance in patients with disorder of consciousness.
Disorder of consciousness (DOC) has various etiologies. Here, we report a case in which DOC following general anesthesia was suspected as being due to the first episode of nonconvulsive status epilepticus (NCSE). An elderly man in his 80s underwent uneventful tumor resection surgery under general anesthesia for extramammary Paget's disease. After the procedure, he regained consciousness following anesthesia discontinuation and was extubated. Soon after extubation, however, although his respiratory status remained stable, his level of consciousness deteriorated to a Glasgow Coma Scale (GCS) score of E1V1M1. Head computed tomography and magnetic resonance imaging scans indicated no abnormal findings. Subsequently, involuntary movements were noted in his left upper limb. Suspecting an epilepsy episode, diazepam was administered, leading to an improvement in the level of consciousness (GCS: E4V5M6). Based on the improvement in consciousness after diazepam administration, we strongly suspected NCSE.
意识障碍若未得到恰当干预可导致不可逆的后遗症。因此,意识障碍患者的早期诊断和治疗至关重要。
意识障碍(DOC)有多种病因。在此,我们报告一例病例,全麻后出现的意识障碍被怀疑是由非惊厥性癫痫持续状态(NCSE)的首次发作所致。一名80多岁的老年男性因乳腺外佩吉特病在全身麻醉下顺利接受了肿瘤切除手术。术后,他在停用麻醉药后恢复了意识并拔除了气管插管。然而,拔管后不久,尽管他的呼吸状况保持稳定,但他的意识水平恶化至格拉斯哥昏迷量表(GCS)评分为E1V1M1。头部计算机断层扫描和磁共振成像扫描均未发现异常。随后,发现他的左上肢出现不自主运动。怀疑为癫痫发作,给予地西泮治疗,意识水平有所改善(GCS:E4V5M6)。基于给予地西泮后意识的改善,我们强烈怀疑为NCSE。