• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

推测非惊厥性癫痫持续状态首次发作是全身麻醉结束后意识障碍的原因:一例病例报告。

Presumed first episode of nonconvulsive status epilepticus as the cause of postoperative disorder of consciousness following the completion of general anesthesia: A case report.

作者信息

Tsuzuki Yumi, Ishida Yusuke, Tomino Mikiko

机构信息

Department of Anesthesiology Tokyo Medical University Tokyo Japan.

出版信息

Clin Case Rep. 2023 Sep 27;11(10):e7988. doi: 10.1002/ccr3.7988. eCollection 2023 Oct.

DOI:10.1002/ccr3.7988
PMID:37780924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10533385/
Abstract

KEY CLINICAL MESSAGE

Disorder of consciousness can lead to irreversible sequelae without proper intervention. Consequently, early diagnosis and treatment are of paramount importance in patients with disorder of consciousness.

ABSTRACT

Disorder of consciousness (DOC) has various etiologies. Here, we report a case in which DOC following general anesthesia was suspected as being due to the first episode of nonconvulsive status epilepticus (NCSE). An elderly man in his 80s underwent uneventful tumor resection surgery under general anesthesia for extramammary Paget's disease. After the procedure, he regained consciousness following anesthesia discontinuation and was extubated. Soon after extubation, however, although his respiratory status remained stable, his level of consciousness deteriorated to a Glasgow Coma Scale (GCS) score of E1V1M1. Head computed tomography and magnetic resonance imaging scans indicated no abnormal findings. Subsequently, involuntary movements were noted in his left upper limb. Suspecting an epilepsy episode, diazepam was administered, leading to an improvement in the level of consciousness (GCS: E4V5M6). Based on the improvement in consciousness after diazepam administration, we strongly suspected NCSE.

摘要

关键临床信息

意识障碍若未得到恰当干预可导致不可逆的后遗症。因此,意识障碍患者的早期诊断和治疗至关重要。

摘要

意识障碍(DOC)有多种病因。在此,我们报告一例病例,全麻后出现的意识障碍被怀疑是由非惊厥性癫痫持续状态(NCSE)的首次发作所致。一名80多岁的老年男性因乳腺外佩吉特病在全身麻醉下顺利接受了肿瘤切除手术。术后,他在停用麻醉药后恢复了意识并拔除了气管插管。然而,拔管后不久,尽管他的呼吸状况保持稳定,但他的意识水平恶化至格拉斯哥昏迷量表(GCS)评分为E1V1M1。头部计算机断层扫描和磁共振成像扫描均未发现异常。随后,发现他的左上肢出现不自主运动。怀疑为癫痫发作,给予地西泮治疗,意识水平有所改善(GCS:E4V5M6)。基于给予地西泮后意识的改善,我们强烈怀疑为NCSE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/0be6ee00a975/CCR3-11-e7988-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/d63c3df9b255/CCR3-11-e7988-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/49dcd13ecd86/CCR3-11-e7988-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/0be6ee00a975/CCR3-11-e7988-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/d63c3df9b255/CCR3-11-e7988-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/49dcd13ecd86/CCR3-11-e7988-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/10533385/0be6ee00a975/CCR3-11-e7988-g003.jpg

相似文献

1
Presumed first episode of nonconvulsive status epilepticus as the cause of postoperative disorder of consciousness following the completion of general anesthesia: A case report.推测非惊厥性癫痫持续状态首次发作是全身麻醉结束后意识障碍的原因:一例病例报告。
Clin Case Rep. 2023 Sep 27;11(10):e7988. doi: 10.1002/ccr3.7988. eCollection 2023 Oct.
2
Case Report: Hypopituitarism Presenting With Nonconvulsive Status Epilepticus.病例报告:以非惊厥性癫痫持续状态为表现的垂体功能减退症
Front Neurol. 2021 Sep 22;12:715885. doi: 10.3389/fneur.2021.715885. eCollection 2021.
3
Assessing the outcomes in patients with nonconvulsive status epilepticus: nonconvulsive status epilepticus is underdiagnosed, potentially overtreated, and confounded by comorbidity.评估非惊厥性癫痫持续状态患者的预后:非惊厥性癫痫持续状态存在诊断不足、可能过度治疗以及受合并症干扰的情况。
J Clin Neurophysiol. 1999 Jul;16(4):341-52; discussion 353. doi: 10.1097/00004691-199907000-00006.
4
Propofol pump controls nonconvulsive status epilepticus in a hepatic encephalopathy patient: A case report.丙泊酚泵控治疗肝性脑病患者非惊厥性癫痫持续状态:一例报告
World J Clin Cases. 2019 Sep 26;7(18):2831-2837. doi: 10.12998/wjcc.v7.i18.2831.
5
Super-refractory nonconvulsive status epilepticus secondary to fat embolism: A clinical, electrophysiological, and pathological study.脂肪栓塞继发的超难治性非惊厥性癫痫持续状态:一项临床、电生理及病理研究
Epilepsy Behav. 2015 Aug;49:184-8. doi: 10.1016/j.yebeh.2015.04.045. Epub 2015 May 16.
6
Endoscope-Assisted Evacuation of an Acute Subdural Hematoma in an Elderly Patient With Refractory Nonconvulsive Status Epilepticus: An Illustrative Case.内镜辅助下老年难治性非惊厥性癫痫持续状态患者急性硬膜下血肿的清除:一例说明性病例
Cureus. 2024 Jul 4;16(7):e63817. doi: 10.7759/cureus.63817. eCollection 2024 Jul.
7
Nonconvulsive status epilepticus and coma.非惊厥性癫痫持续状态和昏迷。
Epilepsia. 2010 Feb;51(2):177-90. doi: 10.1111/j.1528-1167.2009.02297.x. Epub 2009 Sep 10.
8
Clinical phenotypes within nonconvulsive status epilepticus.非惊厥性癫痫持续状态的临床表型。
Epilepsia. 2021 Sep;62(9):e129-e134. doi: 10.1111/epi.16999. Epub 2021 Jul 9.
9
[Clinical characteristics of status epilepticus in an emergency hospital: importance of nonconvulsive status epilepticus].[急诊医院癫痫持续状态的临床特征:非惊厥性癫痫持续状态的重要性]
Rinsho Shinkeigaku. 2008 Apr;48(4):242-8. doi: 10.5692/clinicalneurol.48.242.
10
Nonconvulsive status epilepticus in the elderly.老年人非惊厥性癫痫持续状态。
Rev Neurol (Paris). 2020 Nov;176(9):701-709. doi: 10.1016/j.neurol.2019.12.007. Epub 2020 Mar 10.

引用本文的文献

1
A Case Report on an Unknown Etiology Disorder of Consciousness Following Extubation Despite Thorough Evaluation.一例拔管后意识障碍病因不明的病例报告,尽管已进行全面评估。
Cureus. 2024 Dec 10;16(12):e75513. doi: 10.7759/cureus.75513. eCollection 2024 Dec.

本文引用的文献

1
Diagnosis and Treatment of Status Epilepticus.癫痫持续状态的诊断与治疗
J Epilepsy Res. 2020 Dec 31;10(2):45-54. doi: 10.14581/jer.20008. eCollection 2020 Dec.
2
Non-convulsive status epilepticus in the immediate postoperative period following spine surgery -a case report.脊柱手术后即刻非惊厥性癫痫持续状态-1 例报告。
Korean J Anesthesiol. 2021 Dec;74(6):541-545. doi: 10.4097/kja.20527. Epub 2021 Jan 5.
3
Diagnosis of Coma.昏迷的诊断
Emerg Med Clin North Am. 2021 Feb;39(1):155-172. doi: 10.1016/j.emc.2020.09.009. Epub 2020 Nov 5.
4
Nonconvulsive seizures and nonconvulsive status epilepticus in the neuro ICU should or should not be treated aggressively: A debate.神经重症监护病房中的非惊厥性癫痫发作和非惊厥性癫痫持续状态是否应积极治疗:一场辩论
Clin Neurophysiol Pract. 2019 Aug 9;4:170-177. doi: 10.1016/j.cnp.2019.07.001. eCollection 2019.
5
Non convulsive status epilepticus in the elderly.老年人非惊厥性癫痫持续状态
Geriatr Psychol Neuropsychiatr Vieil. 2019 Mar 1;17(S1):25-30. doi: 10.1684/pnv.2019.0782.
6
Epilepsy in adults.成人癫痫。
Lancet. 2019 Feb 16;393(10172):689-701. doi: 10.1016/S0140-6736(18)32596-0. Epub 2019 Jan 24.
7
Epidemiology, diagnosis, and management of nonconvulsive status epilepticus: Opening Pandora's box.非惊厥性癫痫持续状态的流行病学、诊断与管理:打开潘多拉魔盒
Neurol Clin Pract. 2012 Dec;2(4):275-286. doi: 10.1212/CPJ.0b013e318278be75.
8
Disorders of Consciousness.意识障碍
Phys Med Rehabil Clin N Am. 2017 May;28(2):245-258. doi: 10.1016/j.pmr.2016.12.003. Epub 2017 Mar 1.
9
Current clinical approach to patients with disorders of consciousness.目前针对意识障碍患者的临床治疗方法。
Rev Assoc Med Bras (1992). 2016 Jul;62(4):377-84. doi: 10.1590/1806-9282.62.04.377.
10
Non-convulsive status epilepticus: a practical approach to diagnosis in confused older people.非惊厥性癫痫持续状态:老年意识模糊患者的实用诊断方法
Postgrad Med J. 2015 Nov;91(1081):655-61. doi: 10.1136/postgradmedj-2015-133537. Epub 2015 Sep 23.