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基于扫描电子显微镜数据的人类脑血管丛和室管膜上皮的退行性变化

[Involutional changes in the epithelium of the human cerebral vascular plexuses and ependyma based on scanning electron microscopy data].

作者信息

Kiktenko A I, Orlovskaia D D

出版信息

Arkh Patol. 1986;48(8):40-4.

PMID:3778233
Abstract

Vascular plexi and cerebral ependyma were studied using scanning electron microscope for young, adult and elderly patients. In the elderly the formations mentioned had a number of structural peculiarities, thus, the majority of the epithelial cells in vascular plexus were lacking microvilli, the intercellular spaces were widened having deep grooves in them. Ependymal changes with age were characterized by the disappearance of villi in some groups of cells resulting in the appearance of large zones lacking superficial structures. Special characteristics of Biondi rings in the epithelium of vascular plexus of the elderly is given, as well as their relationship with other structural components. The age-related changes may lead to dysfunction of the hemato-encephalic barrier, that may be significant for the development of aging process.

摘要

使用扫描电子显微镜对年轻、成年和老年患者的血管丛和脑ependyma进行了研究。在老年人中,上述结构有许多结构特点,因此,血管丛中的大多数上皮细胞缺乏微绒毛,细胞间隙增宽并伴有深沟。ependyma随年龄的变化表现为某些细胞群中的绒毛消失,导致出现缺乏表面结构的大片区域。给出了老年人血管丛上皮中Biondi环的特殊特征,以及它们与其他结构成分的关系。与年龄相关的变化可能导致血脑屏障功能障碍,这可能对衰老过程的发展具有重要意义。

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